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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209901-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209901-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$509.90
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Ab209901-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209901-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) - Primary antibody, specific to TNFRSF21, Human IgG1 |
|---|---|
| Synonyms | TNFRSF 21 antibody | BM 018 antibody | BM018 antibody | CD358 antibody | Death receptor 6 antibody | DR 6 antibody | DR6 antibody | MGC31965 antibody | OTTHUMP00000039915 antibody | TNFR related death receptor 6 antibody | TNFRSF21 antibody | TNFRSF21 pro |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to re |
| Host species | Human |
| Specificity | TNFRSF21 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) is a humanized monoclonal antibody that specifically targets TNFRSF21. It can be used in treatment of cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling TNFRSF21 (red) with Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling TNFRSF21 (red) with Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) - Flow Cytometry
Flow Cytometry analysis of huDR6-FL-HEK293-A6 cells labelling TNFRSF21 at 1×105 cell/well can bind Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901), with the EC₅₀ is 0.593 nM.
Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) - SEC
The purity of Abbvie patent anti-TNFRSF21 (anti-TNFRSF21) (Ab209901) is more than 95% verified by HPLC.