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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab190114-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab190114-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab190114-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab190114-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | AB3-7 (anti-CLDN6) - Primary antibody, specific to CLDN6, Human IgG1 |
|---|---|
| Synonyms | Claudin-6 antibody | Claudin6 antibody | CLD6_HUMAN antibody | CLDN 6 antibody | CLDN6 antibody | OTTHUMP00000159248 antibody | Skullin 2 antibody | Skullin antibody | UNQ757/PRO1488 antibody | claudin 6 | Claudin6 | Claudin-6 | CLDN6 | Skullin 2 | skulli |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| Host species | Human |
| Specificity | CLDN6 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
AB3-7 (anti-CLDN6) is a monoclonal antibody targeting the tumor-associated antigen (TAA) Claudin 6 (CLDN6). It has an antitumor activity and can be used in treatment of various cancers. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 78.02 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AB3-7 (anti-CLDN6) (Ab190114) - ELISA
Immobilized Recombinant Human CLDN6-VLP protein at 16.0 μg/mL can bind AB3-7 (anti-CLDN6) (Ab190114) with the EC₅₀ of 46.93 ng/mL.
AB3-7 (anti-CLDN6) (Ab190114) - Flow Cytometry
Flow Cytometry analysis of Hep G2 cells labelling CLDN6 (red) with AB3-7 (anti-CLDN6) (Ab190114) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
AB3-7 (anti-CLDN6) (Ab190114) - SEC
The purity of AB3-7 (anti-CLDN6) (Ab190114) is more than 95% verified by HPLC.
Starting at $109.90
Starting at $89.90