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7-(Diethylamino)coumarin-3-carboxylic Acid - >98.0%, high purity , CAS No.50995-74-9

3 Citations COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
D154333
Grouped product items
SKU Size
Availability
 Price Qty
D154333-50mg
50mg
3
$9.90
D154333-250mg
250mg
3
$13.90
D154333-1g
1g
3
$32.90
D154333-5g
5g
3
$122.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

7-(Diethylamino)coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.

View related series
Membrane Transporter (607) Membrane Transporter/Ion Channel (1822) Monocarboxylate Transporter (13) Six-Membered Heterocyclic Compounds (1696) Spectroscopic reagent (233)

Basic Description

Synonyms MFCD00068721 | HY-D0067 | 7ACC1 | FT-0600960 | HMS560N21 | EN300-246176 | 7-(Diethylamino)coumarin-3-carboxylic acid | Coumarin D 1421 | D4238 | IDI1_006564 | 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylic acid | 7-diethylamino-2-oxo-2H-1-benzopyran-3-ca
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Derivatisation reagent. Fluorescent label for amine modification and protein conjugation. Also used for labeling synthetic peptides for high-throughput detection.
Storage Temp Argon charged
Shipped In Normal
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Coumarins and derivatives
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Coumarins and derivatives
Alternative Parents 1-benzopyrans  Dialkylarylamines  Pyranones and derivatives  Benzenoids  Heteroaromatic compounds  Lactones  Amino acids  Oxacyclic compounds  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Coumarin - Benzopyran - 1-benzopyran - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Pyranone - Pyran - Benzenoid - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Tertiary amine - Lactone - Organoheterocyclic compound - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).
External Descriptors Not available

Associated Targets(Human)

SLC16A3 Tchem Monocarboxylate transporter 4 (2 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF-10A (2462 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SiHa (2051 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-HEP1 (1155 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
WiDr (1835 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HepG2 (196354 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Liver microsomes (16955 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Liver (3974 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC16A3 Tchem Monocarboxylate transporter 4 (196 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
4T1 (1737 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasma (328 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504759796
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504759796
IUPAC Name 7-(diethylamino)-2-oxochromene-3-carboxylic acid
INCHI InChI=1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
InChIKey WHCPTFFIERCDSB-UHFFFAOYSA-N
Smiles CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
Isomeric SMILES CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O
Molecular Weight 261.28
Reaxy-Rn 6145963
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6145963&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number Certificate Type Date Item
G2114360 Certificate of Analysis Apr 03, 2025 D154333
G2114361 Certificate of Analysis Apr 03, 2025 D154333
I1812150 Certificate of Analysis Jul 14, 2022 D154333
I1812149 Certificate of Analysis Jul 14, 2022 D154333
I2215371 Certificate of Analysis Jul 03, 2022 D154333
F2326052 Certificate of Analysis Dec 15, 2021 D154333
C2218397 Certificate of Analysis Dec 15, 2021 D154333
C2218393 Certificate of Analysis Dec 15, 2021 D154333
F2326047 Certificate of Analysis Dec 15, 2021 D154333

Chemical and Physical Properties

Sensitivity Light & Moisture Sensitive
Melt Point(°C) 229 °C
Molecular Weight 261.269 g/mol
XLogP3 3.100
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 4
Exact Mass 261.1 Da
Monoisotopic Mass 261.1 Da
Topological Polar Surface Area 66.800 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 400.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Xiaokan Yu, Weisheng Zhu, Wenao Ouyang, Xiaojia Zhang, Hao Qiu, Zhijun Zhang, Bengang Xing.  (2022)  Protein-Mediated Fluorescence Resonance Energy Transfer (P-FRET) Probe: Fabrication and Hydroxyl Radical Detection†.  PHOTOCHEMISTRY AND PHOTOBIOLOGY,  98  (2): (371-377). 
2. Hao Dai,Ziyi Deng,Yanbo Zeng,Jian Zhang,Yiwen Yang,Qinyan Ma,Wenling Hu,Longhua Guo,Lei Li,Shulin Wan,Haiying Liu.  (2020-06-07)  Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid)..  Journal of hazardous materials,  398  (122854-122854). 
3. Xuequan Liu, Xuequan Sun, Hongyu Zhu, Rubing Yan, Chang Xu, Fangxing Zhu, Ruijie Xu, Jing Xia, He Dong, Bingcheng Yi, Qihui Zhou.  (2024)  A mosquito proboscis-inspired cambered microneedle patch for ophthalmic regional anaesthesia.  Journal of Advanced Research,     

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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