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6-Aminofluorescein - >97%(HPLC), high purity , CAS No.51649-83-3
Fluorescent labeling agent
Basic Description
Synonyms
FCA II | 2-Aminofluorescein | EN300-19304 | SCHEMBL216815 | AS-72049 | Fluorescein amine isomer II | FT-0626460 | PD063765 | Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 6-amino-3',6'-dihydroxy- | AKOS005208671 | Fluorescein, 6-amino- (7CI) | 4-CHLORO
Specifications & Purity
≥97%(HPLC)
Biochemical and Physiological Mechanisms
Fluorescent labeling agent. Labels fullerene-based liposome nanostructures.
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organoheterocyclic compounds
Class
Benzopyrans
Subclass
1-benzopyrans
Intermediate Tree Nodes
Dibenzopyrans
Direct Parent
Xanthenes
Alternative Parents
Diarylethers Phthalides Benzofuranones Isobenzofurans 1-hydroxy-2-unsubstituted benzenoids Lactones Carboxylic acid esters Amino acids and derivatives Oxacyclic compounds Monocarboxylic acids and derivatives Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework
Aromatic heteropolycyclic compounds
Substituents
Xanthene - Diaryl ether - Benzofuranone - Phthalide - Isobenzofuranone - Isocoumaran - Isobenzofuran - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Carboxylic acid ester - Lactone - Amino acid or derivatives - Monocarboxylic acid or derivatives - Ether - Carboxylic acid derivative - Oxacycle - Primary amine - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description
This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
External Descriptors
Not available
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Names and Identifiers
Pubchem Sid
488187334
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488187334
IUPAC Name
5-amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
INCHI
InChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
InChIKey
YOAWSYSKQHLFPM-UHFFFAOYSA-N
Smiles
C1=CC2=C(C=C1N)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
Isomeric SMILES
C1=CC2=C(C=C1N)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
WGK Germany
3
UN Number
3077
Molecular Weight
347.32
Beilstein
51708
Reaxy-Rn
51708
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=51708&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Light Sensitive
Melt Point(°C)
285 °C
Molecular Weight
347.300 g/mol
XLogP3
2.700
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
0
Exact Mass
347.079 Da
Monoisotopic Mass
347.079 Da
Topological Polar Surface Area
102.000 Ų
Heavy Atom Count
26
Formal Charge
0
Complexity
557.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Yongrui Huang, Jia Liu, Xiaomin Sun, Yuehai Peng, Yingni Xu, Sa Liu, Wenjing Song, Li Ren.
(2023)
Self-Assembled Sulfated Hyaluronan Coating Modulates Transforming Growth Factor-Beta1 Penetration for Corneal Scarring Alleviation. ACS Applied Materials & Interfaces,
15
(26):
(31124–31138).
2.
Liu Yipeng, Li Bingyan, Zhang Huixia, Liu Yong, Xie Ping.
(2022)
Detection of Microcystin-LR in the Cells and Natural Lake Water Samples by A Unique Fluorescence-Based Method. JOURNAL OF FLUORESCENCE,
32
(2):
(505-519).
3.
Qidi Zhang, Ming Zou, Wanyu Wang, Jinyan Li, Xiao Liang.
(2021)
Design, Synthesis, and Characterization of Tracers and Development of a Fluorescence Polarization Immunoassay for Rapid Screening of 4,4′-Dinitrocarbanilide in Chicken Muscle. Foods,
10
(8):
(1822).
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3 Citations
F2102074