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ZK824190 hydrochloride - 99%, high purity , CAS No.2629177-12-2

    Grade & Purity:
  • ≥99%
In stock
Item Number
Z646532
Grouped product items
SKU Size
Availability
Price Qty
Z646532-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
Z646532-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$670.90
Z646532-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,350.90

Basic Description

Specifications & Purity ≥99%
Biochemical and Physiological Mechanisms ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator ( uPA ) inhibitor as a potential treatment for multiple sclerosis. IC 50 s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.
Storage Temp Protected from light,Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator ( uPA ) inhibitor as a potential treatment for multiple sclerosis. IC 50 s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.

In Vivo

ZK824190 (2 mg/kg; PO; Rats with EAE model) exhibits a relatively high oral availability and a moderate half time (T 1/2 =2.8 h) . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

Smiles CC[C@@H](OC1=NC(OC2=CC(C3=CC=CC(CN)=C3)=CC=C2)=C(F)C=C1F)C(O)=O.[H]Cl
Molecular Weight 450.86

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMSO : 100 mg/mL (221.80 mM; Need ultrasonic)

Solution Calculators

Reviews

Customer Reviews

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