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Z-LEHD-FMK - ≥98%, high purity , CAS No.210345-04-3

    Grade & Purity:
  • ≥98%
In stock
Item Number
L276266
Grouped product items
SKU Size
Availability
Price Qty
L276266-20μl
20μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$341.90

Irreversible caspase-9 inhibitor

Basic Description

Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Irreversible caspase-9 inhibitor. Selective anti-apoptotic reagent, does not inhibit apoptosis in all biological systems. Neuroprotective. Cell-permeable. Active in vivo.
Storage Temp Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. See SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Peptidomimetics
Subclass Hybrid peptides
Intermediate Tree Nodes Not available
Direct Parent Hybrid peptides
Alternative Parents Histidine and derivatives  Glutamic acid and derivatives  Leucine and derivatives  N-acyl-alpha amino acids and derivatives  Alpha amino acid amides  Beta amino acids and derivatives  Benzyloxycarbonyls  Imidazolyl carboxylic acids and derivatives  Gamma-keto acids and derivatives  Fatty acid methyl esters  N-acyl amines  Dicarboxylic acids and derivatives  Alpha-haloketones  Methyl esters  Carbamate esters  Heteroaromatic compounds  Organic carbonic acids and derivatives  Secondary carboxylic acid amides  Azacyclic compounds  Hydrocarbon derivatives  Organonitrogen compounds  Alkyl fluorides  Organofluorides  Organopnictogen compounds  Organic oxides  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Hybrid peptide - Histidine or derivatives - Glutamic acid or derivatives - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Beta amino acid or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Benzyloxycarbonyl - Gamma-keto acid - Imidazolyl carboxylic acid derivative - Fatty acid ester - Fatty acid methyl ester - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Fatty amide - Fatty acyl - Keto acid - N-acyl-amine - Benzenoid - Azole - Methyl ester - Carbamic acid ester - Alpha-haloketone - Heteroaromatic compound - Imidazole - Carbonic acid derivative - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid ester - Ketone - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Alkyl halide - Organohalogen compound - Carbonyl group - Organic oxide - Organopnictogen compound - Alkyl fluoride - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
External Descriptors Not available

Names and Identifiers

IUPAC Name methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate
INCHI InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)/t22-,23-,24-,25-/m0/s1
InChIKey YXRKBEPGVHOXSV-QORCZRPOSA-N
Smiles CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Molecular Weight 690.7
Reaxy-Rn 31220911
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31220911&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Supplied in DMSO (10 mM)
Molecular Weight 690.700 g/mol
XLogP3 1.600
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 12
Rotatable Bond Count 23
Exact Mass 690.302 Da
Monoisotopic Mass 690.302 Da
Topological Polar Surface Area 224.000 Ų
Heavy Atom Count 49
Formal Charge 0
Complexity 1140.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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