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YODi-1 - ≥95%, 5 mM DMSO Solution, high purity , CAS No.143413-85-8

    Grade & Purity:
  • ≥95%
  • 5 mM DMSO Solution
In stock
Item Number
Y776684
Grouped product items
SKU Size
Availability
Price Qty
Y776684-200μl
200μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90

Excellent high affinity counterstain for DNA and chromatin

Basic Description

Synonyms 1,1'-[1,3-Propanediylbis[(dimethyliminio)-3,1-propanediyl]]bis[4-[(3-methyl-2(3H)-benzoxazolylidene)methyl]-quinolinium,iodine
Specifications & Purity ≥95%, 5 mM DMSO Solution
Biochemical and Physiological Mechanisms Excellent high affinity counterstain for DNA and chromatin.\xa0High fluorescence increase upon binding to nucleic acid. Cell impermeant.
Storage Temp Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Spectral properties:Excitation (nm) 491;Emission (nm) 508

Application:

YODi-1 is a green fluorescent carbocyanine dimeric dye. YODi-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits over a thousand-fold fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make YODi-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. YODi-1 can also be used for the analysis of single molecules of DNA.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Quinolines and derivatives
Subclass Quinolones and derivatives
Intermediate Tree Nodes Not available
Direct Parent Hydroquinolones
Alternative Parents Hydroquinolines  Benzoxazoles  Tertiary alkylarylamines  Benzenoids  Tetraalkylammonium salts  Oxazoles  Heteroaromatic compounds  Oxacyclic compounds  Enamines  Azacyclic compounds  Allylamines  Organopnictogen compounds  Organooxygen compounds  Organic iodide salts  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Dihydroquinolone - Dihydroquinoline - Benzoxazole - Tertiary aliphatic/aromatic amine - Benzenoid - Azole - Oxazole - Quaternary ammonium salt - Tetraalkylammonium salt - Heteroaromatic compound - Tertiary amine - Allylamine - Azacycle - Oxacycle - Enamine - Organic salt - Organic nitrogen compound - Amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic iodide salt - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as hydroquinolones. These are compounds containing a hydrogenated quinoline bearing a ketone group.
External Descriptors cyanine dye - organic iodide salt

Names and Identifiers

IUPAC Name 3-[dimethyl-[3-[4-[(E)-(3-methyl-1,3-benzoxazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azaniumyl]propyl-dimethyl-[3-[4-[(Z)-(3-methyl-1,3-benzoxazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium;tetraiodide
INCHI InChI=1S/C49H58N6O2.4HI/c1-50-44-22-11-13-24-46(44)56-48(50)36-38-26-30-52(42-20-9-7-18-40(38)42)28-15-32-54(3,4)34-17-35-55(5,6)33-16-29-53-31-27-39(41-19-8-10-21-43(41)53)37-49-51(2)45-23-12-14-25-47(45)57-49;;;;/h7-14,18-27,30-31,36-37H,15-17,28-29,32-35H2,1-6H3;4*1H/q+4;;;;/p-4
InChIKey GRRMZXFOOGQMFA-UHFFFAOYSA-J
Smiles CN1C2=CC=CC=C2OC1=CC3=CC=[N+](C4=CC=CC=C34)CCC[N+](C)(C)CCC[N+](C)(C)CCC[N+]5=CC=C(C6=CC=CC=C65)C=C7N(C8=CC=CC=C8O7)C.[I-].[I-].[I-].[I-]
Isomeric SMILES CN\1C2=CC=CC=C2O/C1=C/C3=CC=[N+](C4=CC=CC=C34)CCC[N+](C)(C)CCC[N+](C)(C)CCC[N+]5=CC=C(C6=CC=CC=C65)/C=C\7/N(C8=CC=CC=C8O7)C.[I-].[I-].[I-].[I-]
PubChem CID 6438136
Molecular Weight 1270.65

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Soluble in DMSO
Sensitivity Light sensitive

Citations of This Product

1. Zhicheng Le, Jiang Qian, Haolin Chen, Zepeng He, Runcheng Tan, Hong Liu, Zhenfu Wen, Yi Shi, Zhijia Liu, Yongming Chen.  (2024)  A versatile gemini amphiphile-based platform with STING-activating properties for efficient gene delivery into dendritic cells.  CHEMICAL ENGINEERING JOURNAL,  497  (154513). 

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