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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Y274902-5mg
|
5mg |
2
|
$147.90
|
|
|
Y274902-10mg
|
10mg |
2
|
$246.90
|
|
|
Y274902-25mg
|
25mg |
2
|
$543.90
|
|
|
Y274902-100mg
|
100mg |
2
|
$1,335.90
|
|
Allosteric Hsp70 modulator. Potent anti-tau agent.
| Synonyms | 2-[[3-Ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-1-methyl-pyridinium chloride |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Allosteric Hsp70 modulator. Potent anti-tau agent. MKT-077 analog. Promotes triage functions of Hsp70. Rapidly and potently reduces tau levels ex vivo. Shows antitumor effects in vivo. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
| Pubchem Sid | 504772884 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772884 |
| IUPAC Name | 3-ethyl-5-(3-methyl-1,3-benzothiazol-2-ylidene)-2-[(1-methylpyridin-1-ium-2-yl)methylidene]-1,3-thiazolidin-4-one;chloride |
| INCHI | InChI=1S/C20H20N3OS2.ClH/c1-4-23-17(13-14-9-7-8-12-21(14)2)26-18(19(23)24)20-22(3)15-10-5-6-11-16(15)25-20;/h5-13H,4H2,1-3H3;1H/q+1;/p-1 |
| InChIKey | KEQDCNWQIQWINZ-UHFFFAOYSA-M |
| Smiles | CCN1C(=CC2=CC=CC=[N+]2C)SC(=C3N(C4=CC=CC=C4S3)C)C1=O.[Cl-] |
| PubChem CID | 118703534 |
| Molecular Weight | 417.97 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Aug 17, 2023 | Y274902 | |
| Certificate of Analysis | Aug 17, 2023 | Y274902 | |
| Certificate of Analysis | Aug 17, 2023 | Y274902 | |
| Certificate of Analysis | Aug 17, 2023 | Y274902 |
| Solubility | Soluble in water to 5 mM |
|---|