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YKL-06-062 - 10mM in DMSO, high purity , CAS No.2172617-16-0(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 2172617-16-0(DMSO)
Molecular Weight: 525.69

In stock

Item Number

Y655948

Grouped product items
SKU	Size	Availability	Price	Qty
Y655948-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$308.90

View related series

Compound libraries (12325) Immunology/Inflammation (1929) Salt-inducible Kinase (SIK) (15)

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC 50 of 2.12 nM/1.40 nM/2.86 nM for SIK1 , SIK2 and SIK3 , respectively.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC 50 of 2.12 nM/1.40 nM/2.86 nM for SIK1 , SIK2 and SIK3 , respectively. In Vitro YKL 06-062 (0.0004-16 μM; 3 hours) increases MITF mRNA expression in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. RT-PCRCell Line: Human melanocyte cells, UACC62 melanoma cells Concentration: 0.0004 μM, 0.004 μM, 0.04 μM, 0.4 μM, 4 μM,8 μM,16 μM Incubation Time: 3 hours Result: Unregulated MITF mRNA expression.

Names and Identifiers

Smiles	CC1=C(C(=CC=C1)C)N2CC3=CN=C(N=C3N(C2=O)C4CCCCC4)NC5=CC=C(C=C5)N6CCN(CC6)C
Molecular Weight	525.69

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