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YAP/TAZ inhibitor-2 - 98%, high purity , CAS No.2762617-31-0

COA

Grade & Purity:

≥98%

Cas Number: 2762617-31-0
Molecular Weight: 390.33

In stock

Item Number

Y649740

Grouped product items
SKU	Size	Availability	Price
Y649740-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
Y649740-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$380.90
Y649740-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$750.90
Y649740-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,200.90

View related series

Stem Cell/Wnt (1019) YAP (38)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC 50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC 50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity In Vitro YAP/TAZ inhibitor-2 (compound 5) (0-20000 nM; 24 h) shows antiproliferative activity with an IC 50 value of 5.33 nM in NCI-H226 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo YAP/TAZ inhibitor-2 (0.5, 2, 5, 50 mg/kg; p.o.; daily for 28 days) shows anti-tumor activity with no significant body weight loss during the treatment in BALB/c nude mice (NCI-H226 xenograft model) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC 50 : 3 nM (TEAD-YAP/TAZ)

Names and Identifiers

Smiles	C=C(F)C(N1CC(N2N=C(C3=CC=C(C(F)(F)F)C=C3)C4=CC=CN=C42)C1)=O
Molecular Weight	390.33

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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