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Xanthophyll - 10mM in DMSO, high purity , CAS No.127-40-2

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
X421127
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X421127-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$88.90

Basic Description

Synonyms Lutein | XANTHOPHYLL | 127-40-2 | Bo-Xan | Vegetable lutein | Vegetable luteol | all-trans-Lutein | trans-Lutein | Xantofyl | Lutein ester | all-trans-(+)-Xanthophyll | FloraGLO | FloraGLO Lutein | Lutein A | Lutein, all-trans- | all-trans-Xanthophyll | Lutamax | Oro Glo 7 | beta,epsilon-Ca
Specifications & Purity 10mM in DMSO
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Xanthophyll is one of the most widespread carotenoid alcohols in nature that was originally isolated from egg yolk. It has also been identified via chromatography in algae, nettles, and the petals of many yellow flowers.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Prenol lipids
Subclass Tetraterpenoids
Intermediate Tree Nodes Carotenoids
Direct Parent Xanthophylls
Alternative Parents Secondary alcohols  Hydrocarbon derivatives  
Molecular Framework Aliphatic homomonocyclic compounds
Substituents Xanthophyll - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone.
External Descriptors C40 isoprenoids (tetraterpenes)

Associated Targets(Human)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Prunus domestica (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Capsicum (9 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rubus (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Anethum graveolens (3 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rumex acetosa (57 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
INCHI InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1
InChIKey KBPHJBAIARWVSC-RGZFRNHPSA-N
Smiles CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C
Isomeric SMILES CC1=C(C(C[C@@H](C1)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/[C@H]2C(=C[C@@H](CC2(C)C)O)C)/C)/C
WGK Germany 3
PubChem CID 5281243
Molecular Weight 568.87
Beilstein 2068547

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Light & Air sensitive
Molecular Weight 568.900 g/mol
XLogP3 11.000
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 10
Exact Mass 568.428 Da
Monoisotopic Mass 568.428 Da
Topological Polar Surface Area 40.500 Ų
Heavy Atom Count 42
Formal Charge 0
Complexity 1270.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 9
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 9
Covalently-Bonded Unit Count 1

Citations of This Product

1. Gul Muhammad, Parisa Jahanbakhsh-Bonab, Wenlong Xiong, Yongkun Lv, Shen Zhang, Anqi Zhao, Jaber Jahanbin Sardroodi, Jingliang Xu, Md Asraful Alam.  (2024)  Mechanism of deep eutectic solvent-mediated microalgal biomass disintegration for enhanced lutein extraction.  INDUSTRIAL CROPS AND PRODUCTS,  209  (117940). 
2. Islam Md Monirul, Hassan Mahmood Ul, Ishfaq Muhammad, Ripa Farhana Alam, Nadeem Faisal, Ahmad Zeeshan, Xu Jiuliang, Ning Peng, Li Xuexian.  (2023)  Foliar Glutamine Application Improves Grain Yield and Nutritional Quality of Field-Grown Maize (Zea mays L.) Hybrid ZD958.  JOURNAL OF PLANT GROWTH REGULATION,    (1-14). 
3. Gaoshuai Zhang, Meijing Zhang, Yiqiao Pei, Kun Qian, Jiao Xie, Qun Huang, Suwen Liu, Na Xue, Yujiao Zu, Hao Wang.  (2023)  Enhancing stability of liposomes using high molecular weight chitosan to promote antioxidative stress effects and lipid-lowering activity of encapsulated lutein in vivo and in vitro.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  253  (126564). 
4. Zhenxia Shi, Gaoyuan Kong, Fangfang Wang, Hui Gao, Anran Wei, Sizhu Ren, Xunyou Yan.  (2023)  Improvement in the stability and bioavailability of pumpkin lutein using β-cyclodextrin microcapsules.  Food Science & Nutrition,  11  (6): (3067-3074). 
5. Zhiyu Liu, Songyi Lin, Wenwen Liu, Yoshimasa Nakamura, Yue Tang.  (2023)  Construction of benzyl isothiocyanate-loaded fish skin gelatin-luteolin compound emulsion delivery system, and its digestion and absorption characteristics.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (4): (1864-1873). 
6. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu.  (2022)  Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system.  Analytical Methods,  14  (37): (3632-3637). 
7. Fenghui Pan, Wenxia Cui, Lei Gao, Xiaoting Shi, Haiyan Yang, Yun Hu, Man Li.  (2022)  Serum lutein is a promising biomarker for type 2 diabetes mellitus and diabetic kidney disease in the elderly.  JOURNAL OF CLINICAL LABORATORY ANALYSIS,  36  (4): (e24350). 
8. Li-Hua Pan, Cui-Ling Wu, Shui-Zhong Luo, Jian-Ping Luo, Zhi Zheng, Shao-Tong Jiang, Yan-Yan Zhao, Xi-Yang Zhong.  (2022)  Preparation and characteristics of sucrose-resistant emulsions and their application in soft candies with low sugar and high lutein contents and strong antioxidant activity.  FOOD HYDROCOLLOIDS,  129  (107619). 
9. Jiang Hong, Fan Yahui, Li Juan, Wang Jiaqi, Kong Liyun, Wang Lina, Li Zhaofang, Ma Mei, Shi Xin, Liu Sijiao, Shi Jia, Zhu Hailu, Liu XiaoHong, Ma Le.  (2022)  The Associations of Plasma Carotenoids and Vitamins With Risk of Age-Related Macular Degeneration: Results From a Matched Case-Control Study in China and Meta-Analysis.  Frontiers in Nutrition,   
10. Chengchen Cai, Ming Zhang, Haiming Chen, Wenxue Chen, Weijun Chen, Qiuping Zhong.  (2022)  Enhancement of norisoprenoid and acetoin production for improving the aroma of fermented mango juice by Bacillus subtilis-HNU-B3.  PROCESS BIOCHEMISTRY,  113  (177). 
11. Hai-Feng Jiang, Cheng Chen, Xin-Yuan Jiang, Jing-Lei Shen, Fei Ling, Peng-Fei Li, Gao-Xue Wang.  (2022)  Luteolin in Lonicera japonica inhibits the proliferation of white spot syndrome virus in the crayfish Procambarus clarkii.  AQUACULTURE,  550  (737852). 
12. Zhipeng Qi, Xianyu Fan, Chunyi Zhu, Dongsheng Chang, Jianjun Pei, Linguo Zhao.  (2021)  Overexpression and Characterization of a Novel Plant Carotenoid Cleavage Dioxygenase 1 from Morus notabilis.  CHEMISTRY & BIODIVERSITY,  19  (2): (e202100735). 
13. Dang Qingyuan, Sha Haiyun, Nie Jiyun, Wang Yongzhang, Yuan Yongbing, Jia Dongjie.  (2021)  An apple (Malus domestica) AP2/ERF transcription factor modulates carotenoid accumulation.  Horticulture Research,   
14. Fei-Fei Qi, Tian-You Ma, Ya-Meng Fan, Lan-ling Chu, Yan Liu, Yan Yu.  (2021)  Nanoparticle-based polyacrylonitrile monolithic column for highly efficient micro solid-phase extraction of carotenoids and vitamins in human serum.  JOURNAL OF CHROMATOGRAPHY A,  1635  (461755). 
15. Zhenghan Shi, Yanli Lu, Zetao Chen, Chen Cheng, Jie Xu, Qingqing Zhang, Zupeng Yan, Zisheng Luo, Qingjun Liu.  (2021)  Electrochemical non-enzymatic sensing of glycoside toxins by boronic acid functionalized nano-composites on screen-printed electrode.  SENSORS AND ACTUATORS B-CHEMICAL,  329  (129197). 
16. Huijuan Shangguan, Shan Zhang, Xin Li, Qi Zhou, Jie Shi, Qianchun Deng, Fenghong Huang.  (2020)  Synthesis of lutein esters using a novel biocatalyst of Candida antarctica lipase B covalently immobilized on functionalized graphitic carbon nitride nanosheets.  RSC Advances,  10  (15): (8949-8957). 
17. Lei Wang, Yujie Li, Dong Xiang, Weimin Zhang, Xinpeng Bai.  (2020)  Stability of lutein in O/W emulsion prepared using xanthan and propylene glycol alginate.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  152  (371). 
18. Jia Dongjie, Li Yuchen, Jia Kun, Huang Benchang, Dang Qingyuan, Wang Huimin, Wang Xinyuan, Li Chunyu, Zhang Yugang, Nie Jiyun, Yuan Yongbing.  (2024)  Abscisic acid activates transcription factor module MdABI5–MdMYBS1 during carotenoid-derived apple fruit coloration.  PLANT PHYSIOLOGY,     
19. Shan Zhang, Zhida Sun, David Julian McClements, Bijun Xie, Ruofan Zheng, Qianchun Deng, Yashu Chen.  (2024)  Carotenoids encapsulated in natural flaxseed oil body: Different colloidal interfaces induce their behavior and stability disparity.  FOOD HYDROCOLLOIDS,  156  (110311). 
20. Zi-Ling Li, Xiao-Run Qi, Yi-Heng Xu, Jia-Qi Zhao, Gui-Fu Zuo, Man-Man Wang.  (2025)  Highly efficient and convenient QuEChERS using ZIF-67 derived magnetic nanoporous carbon for determination of carbamate pesticides in various vegetable and fruit samples.  FOOD CHEMISTRY,    (142904). 
21. Qiu Fu, Ying Qin, Xinjia Zhang, Lijian Sun, Jiang Chang.  (2024)  Highly transparent, low haze and ultraviolet to blue light blocking cellulose films tailored by lutein as electronic screen protectors.  INDUSTRIAL CROPS AND PRODUCTS,  217  (118897). 
22. Kaixuan Ke, Ling Guo, Zhipeng Qi, Dou Dou, Han Ma, Xianying Fang, Linguo Zhao.  (2024)  Molecular cloning, expression, and biochemical characterization of carotenoid cleavage dioxygenase 1 (LbCCD1) from Lycium barbarum.  Molecular Catalysis,  569  (114561). 
23. Weiwei Cheng, Jiahe Xu, Xiaowen Wang, Xinyang Li, Yufeng Chen, Guoqin Liu, Xuxia Zhou, Yuting Ding, Shulai Liu.  (2024)  Multiple Mechanisms of Haematococcus pluvialis–Derived Carotenoids to Inhibit Glycidyl Ester Formation in Rice Oil and a Chemical Model at High Temperatures.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  72  (34): (19177-19186). 
24. Yuxiang Wang, Benguo Liu, Yuling Ma, Chunyan Wang, Hanjun Ma, Sheng Geng.  (2025)  Oil/water interface behavior of hesperidin methylchalcone and its application in nano-emulsions.  FOOD CHEMISTRY,  463  (141235). 
25. Xuening Song, Yingting Luo, Wenduo Zhao, Simiao Liu, Yuzhuo Wang, Hao Zhang.  (2024)  Preparation and Characterization of Lutein Co-Amorphous Formulation with Enhanced Solubility and Dissolution.  Foods,  13  (13): (2029). 
26. Jingwen Yu, Xiangwei Xiao, Baiying Chen, Zeyuan Deng, Xuan Chen, Yawei Fan, Hongyan Li.  (2024)  Synergistic and Antagonistic Activity of Selected Dietary Phytochemicals against Oxidative Stress-Induced Injury in Cardiac H9c2 Cells via the Nrf2 Signaling Pathway.  Foods,  13  (15): (2440). 
27. Yves Harimana, Bertrand Muhoza, Philip Munyandamutsa, Javzan Gankhuyag, Shuang Zhang, Yang Li.  (2024)  Unraveling the binding mechanism between soybean protein isolate and selected bioactive compounds.  FOOD CHEMISTRY,    (139031). 

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