Basic Description

Specifications & Purity	UltraBio™, ≥99%
Biochemical and Physiological Mechanisms	Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Grade	UltraBio™
Product Description	Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors: Guanine deamination by guanine deaminase Hypoxanthine conversion by xanthine oxidoreductase Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea. Application: Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems: yeast culture human cell line culture recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Imidazopyrimidines
    - Subclass Purines and purine derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Imidazopyrimidines
Subclass	Purines and purine derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Xanthines
Alternative Parents	6-oxopurines Alkaloids and derivatives Pyrimidones Vinylogous amides Imidazoles Heteroaromatic compounds Ureas Lactams Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Xanthine - 6-oxopurine - Purinone - Alkaloid or derivatives - Pyrimidone - Pyrimidine - Azole - Imidazole - Heteroaromatic compound - Vinylogous amide - Lactam - Urea - Azacycle - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as xanthines. These are purine derivatives with a ketone group conjugated at carbons 2 and 6 of the purine moiety.
External Descriptors	a small molecule
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	3,7-dihydropurine-2,6-dione
INCHI	InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
InChIKey	LRFVTYWOQMYALW-UHFFFAOYSA-N
Smiles	C1=NC2=C(N1)C(=O)NC(=O)N2
Isomeric SMILES	C1=NC2=C(N1)C(=O)NC(=O)N2
WGK Germany	3
RTECS	ZD7700000
PubChem CID	1188
Molecular Weight	152.11
Beilstein	8733
Reaxy-Rn	609330

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	1 M NaOH: 0.1 M, clear, colorless to light yellow
Sensitivity	light sensitive
Molecular Weight	152.110 g/mol
XLogP3	-0.700
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	152.033 Da
Monoisotopic Mass	152.033 Da
Topological Polar Surface Area	86.900 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	217.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yingkun Shi, Zijun Niu, Argenis Rodas-Gonzalez, Songlei Wang, Yihua Wang, Lingfan Yang. (2024) An electrochemical adsorption-catalysis sensor based on 2D MXene/g-C3N4 doped with Au-COOH for selective detection of GMP in meat. CHEMICAL ENGINEERING JOURNAL, 500 (155893).
2. Wenxin Bao, Luyuan Tian, Hao Wang, Aidong Tang, Huaming Yang. (2024) Breaking through the pH Limitation of Fe1–xS Nanozymes Using Component-Modulated Coupled Nanoclay. INORGANIC CHEMISTRY, 63 (7): (3366-3375).
3. Shuwen Zhou, Huijuan Cai, Zhiyong Tang, Siyu Lu. (2024) Carbon dots encapsulated zeolitic imidazolate framework-8 as an enhanced multi-antioxidant for efficient cytoprotection to HK-2 cells. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 676 (726).
4. Yingzhu Lian, Guiming Fu, Xinmei Liang, Xinchao He, Jin Xu, Haowei Fan, Yin Wan. (2024) Combination of Artemisia selengensis Turcz leaves polysaccharides and dicaffeoylquinic acids could be a potential inhibitor for hyperuricemia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 271 (132687).
5. Yamin Liu, Xunjiang Wang, Jiaojiao Wei, Kangning Fu, Yilin Chen, Linnan Li, Zhengtao Wang, Li Yang. (2024) Comprehensive Profiling of Amino Acids and Derivatives in Biological Samples: A Robust UHPLC-MS/MS Method for Investigating Acute Lung Injury. JOURNAL OF CHROMATOGRAPHY A, (464816).
6. Chengyu Zhang, Weifan Dang, Jingjing Zhang, Cong Wang, Peng Zhong, Zhaoxin Wang, Yufan Yang, Yuefei Wang, Xiaohui Yan. (2024) Development of a paper-based transcription aptasensor for convenient urinary uric acid self-testing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 271 (132241).
7. Bin Cheng, Jie Zhou, Xu Wang, Zihan He, Zhengyi Xu, Jian Wang, Junyu Chen, Zhou Zhu, Weifeng Zhao, Qianbing Wan, Xibo Pei. (2024) Dual-responsive metal polyphenol network nanosheets for diabetic wound healing. CHEMICAL ENGINEERING JOURNAL, 494 (153071).
8. Yuhong Xiao, Yizhe He, Da Zhong, Bo Liu, ZhiBo Tang, Xiaoyong Lan, YiYang Dong, Huixian Du, Yu Liu, Jun Luo. (2025) Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury. ACS Nano, 19 (12): (11841-11860).
9. Jiaojiao Yuan, Cheng Yang, Jialing Cao, Lianfu Zhang. (2024) Effects of Low Temperature–Ultrasound–Papain (LTUP) Combined Treatments on Purine Removal from Pork Loin and Its Influence on Meat Quality and Nutritional Value. Foods, 13 (8): (1215).
10. Kai-lin Chen, Dong-dong Xie, Man-ping Luo, Bing Liu, Yang Li, Yu-jie Zhao, Xiao-xiao Zhao, Jia-mei Pei, Yong-gang Ding, Zai-Ping Feng, Bei Wang, Xin-guo Zhang. (2024) Functional Food Potential of Chrysanthemum morifolium, Perilla frutescens, and Sophora japonica in Managing Hyperuricemia through Dual Enzyme Inhibition. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 72 (46): (25879-25894).
11. Bihui Zhu, Zhenyang Zhao, Sujiao Cao, Yimin Sun, Liyun Wang, Songya Huang, Chong Cheng, Lang Ma, Li Qiu. (2024) Highly spontaneous spin polarization engineering of single-atom artificial antioxidases towards efficient ROS elimination and tissue regeneration. Nanoscale,
12. Huixian Wang, Xiaolu Zhou, Yixuan Liu, Wenxuan Xie, Derui Yang, Dongxue Huo, Quan Guo, Ruimin Wang. (2024) Identification and molecular docking of xanthine oxidase and α-glucosidase inhibitors in Opuntia ficus-indica fruit. JOURNAL OF FOOD SCIENCE,
13. Rui Wang, Pei-Feng Guo, Jing Nie, Xing Hu, Yu-Wei Wu, Shu Zhu, Bo-Ru Chen, Jian Li, Xin-An Zeng, Fei-Yue Xu. (2024) Inhibitory mechanism of xanthine oxidase by 6-, 8- and 10-gingerol: Enzyme kinetics, multi-spectroscopy and molecular simulations. JOURNAL OF MOLECULAR LIQUIDS, 410 (125605).
14. Huixian Wang, Xingqiao He, Juanni Li, Jintao Wu, Shuaiming Jiang, Hui Xue, Jiachao Zhang, Rajesh Jha, Ruimin Wang. (2024) Lactic acid bacteria fermentation improves physicochemical properties, bioactivity, and metabolic profiles of Opuntia ficus-indica fruit juice. FOOD CHEMISTRY, 453 (139646).
15. Minghao Liu, Kaiyu Wang, Yan Zhang, Xue Zhou, Wannan Li, Weiwei Han. (2025) Mechanistic Study of Protein Interaction with Natto Inhibitory Peptides Targeting Xanthine Oxidase: Insights from Machine Learning and Molecular Dynamics Simulations. Journal of Chemical Information and Modeling,
16. He-He Tian, Yu-Lian Li, Xu-Song Wang, Xu-Hui Huang, Yu-Ying Zhang, Zi-Chun Zhang, Da-Yong Zhou, Lei Qin. (2024) Metabolomic insights into the effects of seasonal shifts on the dynamic variation of non-volatile compounds of abalone (Haliotis discus hannai). FOOD CHEMISTRY, 449 (139197).
17. Hongyu Chen, Mengjie Hou, Ruiting Li, Manman Sun, Wenping Zhu, Weijie Yang, Zengchen Liu, Yahong Chen. (2025) Multi-cascade signal amplification and structure modulation strategy for highly sensitive and selective detection of cysteine using bovine serum albumin-stabilized gold nanoflowers as signal mediator. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 307 (142142).
18. Cailin Qiao, Xinrou Wang, Yuwei Gao, Yi Ma, Huibo Luo, Suyi Zhang, Danqun Huo, Changjun Hou. (2024) Protecting Saccharomyces cerevisiae Cells with Nanozymes to Increase Alcohol Production. ACS Applied Nano Materials, 7 (8): (9375-9387).
19. Xiao-Yang Shi, Yun-Chuan Li, Lei Yu, Bo-Huai Xiao, Gong-Ming Qian, Jing Guo. (2024) Purines recognition and quantitative analysis by surface-enhanced Raman spectroscopy. MICROCHEMICAL JOURNAL, 199 (110202).
20. Hu Rui, Wu Yijun, He Haoliang, Chen Wentao, Xiang Leiwen, Huang Dihui. (2024) Simultaneous Determination of Nine Gout Factors in Cooked Foods. Food Analytical Methods, (1-9).
21. Li Zhang, Hao-li Wang, Ya-fang Zhang, Xin-tao Mao, Ting-ting Wu, Zhi-hui Huang, Wan-jun Jiang, Ke-qi Fan, Dan-dan Liu, Bing Yang, Mei-hui Zhuang, Guang-ming Huang, Yinming Liang, Shu Jeffrey Zhu, Jiang-yan Zhong, Guang-yin Xu, Xiao-ming Li, Qian Cao, Yi-yuan Li, Jin Jin. (2024) Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon. Cell Metabolism,
22. Maiquan Li, Cui Li, Tiantian Tao, Wenlan Li, Manjun Kang, Peitao Fu, Xia Liu, Wei Quan, Mingzhi Zhu, Zhonghua Liu. (2025) Study on the synergistical effects of characteristic compounds in Osmanthus black tea against xanthine oxidase based on multispectral analysis combined with in silico studies. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 308 (142479).
23. Liu Hong-Zhi, Shu Xiao-Xuan, Huang Mingjie, Wu Bing-Bing, Chen Jie-Jie, Wang Xi-Sheng, Li Hui-Lin, Yu Han-Qing. (2024) Tailoring d-band center of high-valent metal-oxo species for pollutant removal via complete polymerization. Nature Communications, 15 (1): (1-11).
24. Qianxu Wang, Jiarui Liang, Qianhui Zou, Wenxiu Wang, Guiming Yan, Rui Guo, Tian Yuan, Yutang Wang, Xuebo Liu, Zhigang Liu. (2024) Tryptophan Metabolism-Regulating Probiotics Alleviate Hyperuricemia by Protecting the Gut Barrier Integrity and Enhancing Colonic Uric Acid Excretion. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 72 (48): (26746-26761).
25. Qi Sun, Shiji Miao, Wenlong Yu, En-Yu Jiang, Mixue Gong, Genyan Liu, Xiaogang Luo, Ming-Zhi Zhang. (2025) Visual detection of uric acid in serum through catalytic oxidation by a novel cellulose membrane biosensor with schiff base immobilized uricase. BIOSENSORS & BIOELECTRONICS, 268 (116912).

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SKU	Size	Availability	Price
X755591-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$73.90
X755591-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$164.90
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Xanthine - UltraBio™, ≥99%, high purity , CAS No.69-89-6