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Wilforine - 98%, high purity , CAS No.11088-09-8

COA

Grade & Purity:

≥98%

Cas Number: 11088-09-8
Molecular Weight: 867.85
PubChem CID: 601100

In stock

Item Number

W412627

Grouped product items
SKU	Size	Availability	Price
W412627-1mg	1mg	3	$49.90
W412627-5mg	5mg	2	$121.90
W412627-10mg	10mg	2	$182.90
W412627-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$316.90
W412627-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$445.90

P-gp Inhibitors

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Terpenoids (27)

Basic Description

Synonyms	Wilforine \| 26-Deoxywilfordine \| 11088-09-8 \| [20,22,23,25-tetraacetyloxy-21-(acetyloxymethyl)-26-hydroxy-3,15,26-trimethyl-6,16-dioxo-2,5,17-trioxa-11-azapentacyclo[16.7.1.01,21.03,24.07,12]hexacosa-7(12),8,10-trien-19-yl] benzoate \| ZOCKGJZEUVPPPI-UHFFFAOYSA-N \|
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Wilforine (WR), a sesquiterpene pyridine alkaloid found in T. wilfordii plants, significantly inhibits the efflux activity of P-glycoprotein (P-gp).
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information Wilforine Wilforine (WR), a sesquiterpene pyridine alkaloid found in T. wilfordii plants, significantly inhibits the efflux activity of P-glycoprotein (P-gp) . Targets P-gp

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Prenol lipids
    - Subclass Terpene lactones

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Prenol lipids
Subclass	Terpene lactones
Intermediate Tree Nodes	Not available
Direct Parent	Terpene lactones
Alternative Parents	Agarofurans Benzoic acid esters Pyridinecarboxylic acids Benzoyl derivatives Oxepanes Monosaccharides Tetrahydrofurans Tertiary alcohols Heteroaromatic compounds Carboxylic acid esters Cyclic alcohols and derivatives Lactones Dialkyl ethers Azacyclic compounds Oxacyclic compounds Carbonyl compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Terpene lactone - Agarofuran - Sesquiterpenoid - Benzoate ester - Pyridine carboxylic acid - Benzoic acid or derivatives - Benzoyl - Oxepane - Benzenoid - Monosaccharide - Pyridine - Monocyclic benzene moiety - Cyclic alcohol - Tetrahydrofuran - Tertiary alcohol - Heteroaromatic compound - Lactone - Carboxylic acid ester - Carboxylic acid derivative - Oxacycle - Azacycle - Dialkyl ether - Ether - Organoheterocyclic compound - Alcohol - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxygen compound - Organopnictogen compound - Organic oxide - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	[20,22,23,25-tetraacetyloxy-21-(acetyloxymethyl)-26-hydroxy-3,15,26-trimethyl-6,16-dioxo-2,5,17-trioxa-11-azapentacyclo[16.7.1.01,21.03,24.07,12]hexacosa-7(12),8,10-trien-19-yl] benzoate
INCHI	InChI=1S/C43H49NO18/c1-21-16-17-29-28(15-12-18-44-29)39(52)55-19-40(7)30-31(56-23(3)46)35(58-25(5)48)42(20-54-22(2)45)36(59-26(6)49)32(60-38(51)27-13-10-9-11-14-27)34(61-37(21)50)41(8,53)43(42,62-40)33(30)57-24(4)47/h9-15,18,21,30-36,53H,16-17,19-20H2,1-8H3
InChIKey	ZOCKGJZEUVPPPI-UHFFFAOYSA-N
Smiles	CC1CCC2=C(C=CC=N2)C(=O)OCC3(C4C(C(C5(C(C(C(C(C5(C4OC(=O)C)O3)(C)O)OC1=O)OC(=O)C6=CC=CC=C6)OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C)C
Isomeric SMILES	CC1CCC2=C(C=CC=N2)C(=O)OCC3(C4C(C(C5(C(C(C(C(C5(C4OC(=O)C)O3)(C)O)OC1=O)OC(=O)C6=CC=CC=C6)OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C)C
PubChem CID	601100
Molecular Weight	867.85

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
B2426624	Certificate of Analysis	Jan 18, 2024	W412627
B2426650	Certificate of Analysis	Jan 18, 2024	W412627
B2426622	Certificate of Analysis	Jan 18, 2024	W412627
B2426623	Certificate of Analysis	Jan 18, 2024	W412627
B2426625	Certificate of Analysis	Jan 18, 2024	W412627
B2426649	Certificate of Analysis	Jan 18, 2024	W412627

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 100 mg/mL (115.22 mM); Water: Insoluble; Ethanol: Insoluble;
Sensitivity	Light sensitive
Molecular Weight	867.800 g/mol
XLogP3	2.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	19
Rotatable Bond Count	14
Exact Mass	867.295 Da
Monoisotopic Mass	867.295 Da
Topological Polar Surface Area	253.000 Å²
Heavy Atom Count	62
Formal Charge	0
Complexity	1800.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	12
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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