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WAY 316606 hydrochloride - 98%, high purity , CAS No.1781835-02-6

COA

Grade & Purity:

≥98%

Cas Number: 1781835-02-6
Molecular Weight: 484.94
PubChem CID: 25186563
PubChem SID: 504770010

In stock

Item Number

W286811

Grouped product items
SKU	Size	Availability	Price
W286811-5mg	5mg	2	$146.90
W286811-10mg	10mg	2	$226.90
W286811-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$508.90
W286811-50mg	50mg	2	$950.90
W286811-100mg	100mg	1	$1,711.90

Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling

Basic Description

Synonyms	5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC50= 0.65μM); prevents sFRP-1 from interacting with Wnt and thus increases Wnt signaling. Increases total bone area in a murine calvarial organ culture assay.We are aware of a study inPLOS Biologywh
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzenesulfonamides

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzenesulfonamides
Intermediate Tree Nodes	Not available
Direct Parent	Benzenesulfonamides
Alternative Parents	Trifluoromethylbenzenes Benzenesulfonyl compounds Piperidines Organosulfonamides Sulfones Aminosulfonyl compounds Dialkylamines Azacyclic compounds Organofluorides Organic oxides Hydrochlorides Hydrocarbon derivatives Alkyl fluorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Benzenesulfonamide - Trifluoromethylbenzene - Benzenesulfonyl group - Piperidine - Organosulfonic acid amide - Sulfone - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Secondary aliphatic amine - Secondary amine - Azacycle - Organoheterocyclic compound - Alkyl fluoride - Hydrochloride - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Alkyl halide - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504770010
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504770010
IUPAC Name	5-(benzenesulfonyl)-N-piperidin-4-yl-2-(trifluoromethyl)benzenesulfonamide;hydrochloride
INCHI	InChI=1S/C18H19F3N2O4S2.ClH/c19-18(20,21)16-7-6-15(28(24,25)14-4-2-1-3-5-14)12-17(16)29(26,27)23-13-8-10-22-11-9-13;/h1-7,12-13,22-23H,8-11H2;1H
InChIKey	YLOYHLUHXQJNGO-UHFFFAOYSA-N
Smiles	C1CNCCC1NS(=O)(=O)C2=C(C=CC(=C2)S(=O)(=O)C3=CC=CC=C3)C(F)(F)F.Cl
Isomeric SMILES	C1CNCCC1NS(=O)(=O)C2=C(C=CC(=C2)S(=O)(=O)C3=CC=CC=C3)C(F)(F)F.Cl
PubChem CID	25186563
Molecular Weight	484.94

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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5 results found

Lot Number	Certificate Type	Date	Item
H2224329	Certificate of Analysis	Jun 09, 2025	W286811
H2224332	Certificate of Analysis	Jun 09, 2025	W286811
H2224331	Certificate of Analysis	Jun 09, 2025	W286811
H2224333	Certificate of Analysis	Jun 09, 2025	W286811
H2224330	Certificate of Analysis	Jun 09, 2025	W286811

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 9.7, Max Conc. mM: 20
Molecular Weight	484.900 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	484.051 Da
Monoisotopic Mass	484.051 Da
Topological Polar Surface Area	109.000 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	747.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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