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vMIP-II, Antagonist of CCR1;Antagonist of CCR2;Antagonist of CCR5;Antagonist of CCR8;Antagonist of CXCR4, CAS No.rp175391, Antagonist of CCR1;Antagonist of CCR2;Antagonist of CCR5;Antagonist of CCR8;Antagonist of CXCR4

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Item Number
rp175391
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rp175391-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
rp175391-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90

Basic Description

Product Name vMIP-II, Antagonist of CCR1;Antagonist of CCR2;Antagonist of CCR5;Antagonist of CCR8;Antagonist of CXCR4, CAS No.rp175391
Synonyms viral macrophage inflammatory protein-II
Grade Moligand™
Specifications & Purity Moligand™
Action Type ANTAGONIST
Mechanism of action Antagonist of CCR1;Antagonist of CCR2;Antagonist of CCR5;Antagonist of CCR8;Antagonist of CXCR4

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic Polymers
Class Polypeptides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Polypeptides
Alternative Parents Cyclic peptides  Macrolactams  Alpha amino acid amides  Benzene and substituted derivatives  Fatty amides  Secondary carboxylic acid amides  Secondary alcohols  Primary carboxylic acid amides  Amino acids  Organic disulfides  Lactams  Guanidines  Propargyl-type 1,3-dipolar organic compounds  Azacyclic compounds  Carboximidamides  Carboxylic acids  Monocarboxylic acids and derivatives  Organopnictogen compounds  Organic oxides  Carbonyl compounds  Monoalkylamines  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Polypeptide - Cyclic alpha peptide - Macrolactam - Alpha-amino acid amide - Alpha-amino acid or derivatives - Monocyclic benzene moiety - Benzenoid - Fatty amide - Fatty acyl - Guanidine - Lactam - Primary carboxylic acid amide - Organic disulfide - Amino acid or derivatives - Secondary alcohol - Secondary carboxylic acid amide - Amino acid - Carboxamide group - Carboxylic acid derivative - Carboxylic acid - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Monocarboxylic acid or derivatives - Amine - Organic oxygen compound - Organic nitrogen compound - Alcohol - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Primary aliphatic amine - Carbonyl group - Primary amine - Organonitrogen compound - Organooxygen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available

Associated Targets(Human)

CXCR4 Tclin C-X-C chemokine receptor type 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CCR2 Tchem C-C chemokine receptor type 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CCR5 Tclin C-C chemokine receptor type 5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CCR1 Tchem C-C chemokine receptor type 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CCR8 Tchem C-C chemokine receptor type 8 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Storage and Shipping

CAS rp175391

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names viral macrophage inflammatory protein-II
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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