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Basic Description
| Synonyms | 4-Vinylcyclohexene dioxide | 106-87-6 | 4-Vinyl-1-cyclohexene dioxide | 4-Vinylcyclohexene diepoxide | 3-(oxiran-2-yl)-7-oxabicyclo[4.1.0]heptane | VINYLCYCLOHEXENE DIOXIDE | Vinyl cyclohexene dioxide | 4-Vinyl-1-cyclohexene diepoxide | Vinyl cyclohexene diepoxide | 1-Viny |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Vinylcyclohexene dioxide (VCD) is used to study toxicity as an ovotoxin,and it's also used to understand its mechanisms of toxicity towards ovarian follicles and effects on epithelial differentiation. |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Organoheterocyclic compounds
- Class Oxepanes
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Superclass
Organoheterocyclic compounds
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Oxepanes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Oxepanes |
| Alternative Parents | Oxacyclic compounds Epoxides Dialkyl ethers Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Oxepane - Oxacycle - Ether - Oxirane - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as oxepanes. These are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. |
| External Descriptors | epoxide |
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Associated Targets(Human)
ESR1
Tclin
Estrogen receptor alpha (17718 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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THRB
Tclin
Thyroid hormone receptor beta-1 (7926 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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NR1H4
Tclin
Bile acid receptor FXR (6228 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CBX1
Tbio
Chromobox protein homolog 1 (92434 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 3-(oxiran-2-yl)-7-oxabicyclo[4.1.0]heptane |
|---|---|
| INCHI | InChI=1S/C8H12O2/c1-2-6-7(10-6)3-5(1)8-4-9-8/h5-8H,1-4H2 |
| InChIKey | OECTYKWYRCHAKR-UHFFFAOYSA-N |
| Smiles | C1CC2C(O2)CC1C3CO3 |
| Isomeric SMILES | C1CC2C(O2)CC1C3CO3 |
| WGK Germany | 1 |
| RTECS | RN8640000 |
| PubChem CID | 7833 |
| UN Number | 2810 |
| Packing Group | I |
| Molecular Weight | 140.18 |
| Beilstein | 106071 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Refractive Index | 1.477-1.479 |
|---|---|
| Flash Point(°F) | 224.6 °F |
| Flash Point(°C) | 107°C |
| Boil Point(°C) | 230-232°C |
| Molecular Weight | 140.180 g/mol |
| XLogP3 | 0.800 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 140.084 Da |
| Monoisotopic Mass | 140.084 Da |
| Topological Polar Surface Area | 25.100 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 157.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 4 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
| 1. Bian Fuping, Li Xiaoquan, Zhao Jihe, Hu Jiwen, Gui Xuefeng, Li Shi, Lin Shudong. (2023) One-step synthesis of epoxy-based silicon prepolymers and its application in UV-curable coating. Journal of Coatings Technology and Research, 20 (1): (321-331). |
| 2. Fuping Bian, Xiaoquan Li, Jihe Zhao, Xuefeng Gui, Jiwen Hu, Shi Li, Shudong Lin. (2022) Synthesis of epoxy-based silicone prepolymers with UV/moisture dual curability for applications in anti-graffiti coatings. REACTIVE & FUNCTIONAL POLYMERS, 180 (105396). |
| 3. Ting Zhang, Ying Chen, Yang Yang, Zhonghui Wang, Qi Pan, Sichong Xu, Zuyue Sun. (2017) The potentiality of two-dimensional preantral follicle culture as an in vitro model in predicting premature ovarian failure. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 69 (477). |
| 4. Ting Zhang, Dawei Yan, Yang Yang, Aicui Ma, Lei Li, Zhonghui Wang, Qi Pan, Zuyue Sun. (2016) The comparison of animal models for premature ovarian failure established by several different source of inducers. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 81 (223). |
| 5. Yingzi Liu, Meina Li, Fan Zhang, Anwei Zhu, Guoyue Shi. (2015) Development of Au Disk Nanoelectrode Down to 3 nm in Radius for Detection of Dopamine Release from a Single Cell. ANALYTICAL CHEMISTRY, 87 (11): (5531–5538). |
| 6. Meina Li, Yingzi Liu, Shushu Ding, Anwei Zhu, Guoyue Shi. (2014) In situ synthesis of poly(ionic liquid)–Pt nanoparticle composite in glass capillary for the electrocatalytic reduction of oxygen. ANALYST, 139 (22): (5964-5969). |
| 7. Juan Deng, Juan Qin, Guolin Song, Chenghai Li, Wentao Tang, Yilin Tang, Xinfang Xiao, Liu Wu, Sicheng He, Yiqing Zhou, Junfen Li, Yan Wang. (2024) The potential of low-intensity pulsed ultrasound to apply the long-term ovary protection from injury induced by 4-vinylcyclohexene diepoxide through inhibiting granulosa cell apoptosis. Bioengineering & Translational Medicine, (e10744). |
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