Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
V286750-5mg
|
5mg |
2
|
$55.90
|
|
|
V286750-10mg
|
10mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$85.90
|
|
|
V286750-25mg
|
25mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$164.90
|
|
|
V286750-50mg
|
50mg |
2
|
$295.90
|
|
|
V286750-100mg
|
100mg |
2
|
$532.90
|
|
VHL ligand with PEG linker and terminal amine for onward chemistry
| Synonyms | VH 032 - linker 9 | (2S,4R)-1-((S)-2-(2-(2-Aminoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
|---|---|
| Specifications & Purity | ≥95%(HPLC) |
| Biochemical and Physiological Mechanisms | The biochemical mechanism was changed to a functionalized von-Hippel-Lindau (VHL) protein ligand for research and development; an E3 ligase ligand and a PEG linker were incorporated to bind to the target protein ligand. |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
VHL ligand with PEG linker and terminal amine for onward chemistry |
| Pubchem Sid | 504773546 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504773546 |
| IUPAC Name | (2S,4R)-1-[(2S)-2-[[2-(2-aminoethoxy)acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;dihydrochloride |
| INCHI | InChI=1S/C26H37N5O5S.2ClH/c1-16-22(37-15-29-16)18-7-5-17(6-8-18)12-28-24(34)20-11-19(32)13-31(20)25(35)23(26(2,3)4)30-21(33)14-36-10-9-27;;/h5-8,15,19-20,23,32H,9-14,27H2,1-4H3,(H,28,34)(H,30,33);2*1H/t19-,20+,23-;;/m1../s1 |
| InChIKey | DKKLDTGWCBYLGT-YEMZLKFISA-N |
| Smiles | CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCN)O.Cl.Cl |
| PubChem CID | 138991794 |
| Molecular Weight | 604.59 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Sep 12, 2022 | V286750 | |
| Certificate of Analysis | Sep 12, 2022 | V286750 | |
| Certificate of Analysis | Sep 12, 2022 | V286750 | |
| Certificate of Analysis | Sep 12, 2022 | V286750 | |
| Certificate of Analysis | Sep 12, 2022 | V286750 |