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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
V287991-5mg
|
5mg |
2
|
$54.90
|
|
|
V287991-10mg
|
10mg |
2
|
$90.90
|
|
|
V287991-25mg
|
25mg |
2
|
$187.90
|
|
|
V287991-50mg
|
50mg |
2
|
$338.90
|
|
|
V287991-100mg
|
100mg |
2
|
$609.90
|
|
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Synonyms | VH 032 - linker 7 | (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
|---|---|
| Specifications & Purity | ≥95%(HPLC) |
| Biochemical and Physiological Mechanisms | VH 032 amide-alkylC2-amine is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC2 linker with terminal amine ready for conjugation to a target protein ligand. Part o |
| Storage Temp | Protected from light,Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| IUPAC Name | (2S,4R)-1-[(2S)-2-(3-aminopropanoylamino)-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;dihydrochloride |
|---|---|
| INCHI | InChI=1S/C25H35N5O4S.2ClH/c1-15-21(35-14-28-15)17-7-5-16(6-8-17)12-27-23(33)19-11-18(31)13-30(19)24(34)22(25(2,3)4)29-20(32)9-10-26;;/h5-8,14,18-19,22,31H,9-13,26H2,1-4H3,(H,27,33)(H,29,32);2*1H/t18-,19+,22-;;/m1../s1 |
| InChIKey | KPAQKVPFCMFPJU-XUKLEHFWSA-N |
| Smiles | CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCN)O.Cl.Cl |
| PubChem CID | 138991789 |
| Molecular Weight | 574.56 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 10, 2025 | V287991 | |
| Certificate of Analysis | Jun 10, 2025 | V287991 | |
| Certificate of Analysis | Jun 10, 2025 | V287991 | |
| Certificate of Analysis | Jun 10, 2025 | V287991 | |
| Certificate of Analysis | Jun 10, 2025 | V287991 |
| Sensitivity | light sensitive |
|---|