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Uridine 5′-triphosphate trisodium salt hydrate - 95%, high purity , CAS No.19817-92-6

1 Citations COA COA
In stock
Item Number
U406318
Grouped product items
SKU Size
Availability
 Price Qty
U406318-250mg
250mg
3
$9.90
U406318-1g
1g
1
$15.90
U406318-5g
5g
3
$35.90
U406318-25g
25g
2
$109.90
U406318-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

P2Y receptor agonist.

View related series
Class A GPCR (4138) Metabolite (5307) Ribonucleotides and derivatives (5)

Basic Description

Synonyms AS-80622 | Q27279174 | UNII-GM3E161I3C | Uridine-5'-triphosphate trisodium | UTIPINA | NSC-20260 | UTP, Trisodium Salt | uridine-5'-triphosphoricacidtrisodiumsalt | 6-(Trifluoromethyl)-1H-benzo[d][1,2,3]triazol-1-ol | Uridine 5'-triphosphate sodium salt |
Specifications & Purity Moligand™, ≥95%
Biochemical and Physiological Mechanisms Pyrimidine nucleoside triphosphate. Precursor in the enzymatic biosynthesis of RNA. P2Y receptor agonist, used to study ion transport functions of P2Y2 receptors on rat basolateral membranes.
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Application：

UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis.
Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Pyrimidine nucleotides
Subclass Pyrimidine ribonucleotides
Intermediate Tree Nodes Not available
Direct Parent Pyrimidine ribonucleoside triphosphates
Alternative Parents Pentose phosphates  Glycosylamines  Monosaccharide phosphates  Pyrimidones  Alkyl phosphates  Hydropyrimidines  Vinylogous amides  Tetrahydrofurans  Heteroaromatic compounds  Ureas  Secondary alcohols  1,2-diols  Lactams  Oxacyclic compounds  Azacyclic compounds  Hydrocarbon derivatives  Organic oxides  Organic sodium salts  Organonitrogen compounds  Organopnictogen compounds  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyrimidine ribonucleoside triphosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Monosaccharide phosphate - Pentose monosaccharide - Pyrimidone - Hydropyrimidine - Monosaccharide - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Tetrahydrofuran - Vinylogous amide - Heteroaromatic compound - Urea - Secondary alcohol - 1,2-diol - Lactam - Organic alkali metal salt - Organoheterocyclic compound - Azacycle - Oxacycle - Organonitrogen compound - Alcohol - Organopnictogen compound - Organic sodium salt - Organic oxygen compound - Organic salt - Organooxygen compound - Organic oxide - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidine ribonucleoside triphosphates. These are pyrimidine ribobucleotides with triphosphate group linked to the ribose moiety.
External Descriptors Not available

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CSNK1D Tchem Casein kinase I delta (4546 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
S1PR1 Tclin Sphingosine 1-phosphate receptor Edg-1 (5806 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
C5AR1 Tclin C5a anaphylatoxin chemotactic receptor (2677 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U2OS (164939 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CX3CR1 Tchem C-X3-C chemokine receptor 1 (1686 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FPR2 Tchem Lipoxin A4 receptor (3472 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GPR35 Tchem G-protein coupled receptor 35 (2643 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TRIM24 Tchem Transcription intermediary factor 1-alpha (2087 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRPF1 Tchem Peregrin (2217 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK-293T (167025 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Aplnr Apelin receptor (201 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Gpr119 Glucose-dependent insulinotropic receptor (270 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504755925
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504755925
IUPAC Name trisodium;[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
INCHI InChI=1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
InChIKey MMJGIWFJVDOPJF-LLWADOMFSA-K
Smiles [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
WGK Germany 3
Alternate CAS 63-39-8
Molecular Weight 550.09 (anhydrous basis)
Beilstein 3585234
Reaxy-Rn 5373891

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot Number Certificate Type Date Item
D2527427 Certificate of Analysis Mar 21, 2025 U406318
D2527426 Certificate of Analysis Mar 21, 2025 U406318
E2509528 Certificate of Analysis Mar 21, 2025 U406318
E2509529 Certificate of Analysis Mar 21, 2025 U406318
E2509533 Certificate of Analysis Mar 21, 2025 U406318
B2507117 Certificate of Analysis Dec 11, 2024 U406318
J22111238 Certificate of Analysis Jul 02, 2024 U406318
L2409669 Certificate of Analysis Apr 12, 2024 U406318
L2409613 Certificate of Analysis Apr 12, 2024 U406318
B2318245 Certificate of Analysis Feb 24, 2023 U406318
B2318246 Certificate of Analysis Feb 24, 2023 U406318
B2318249 Certificate of Analysis Feb 24, 2023 U406318
B2318239 Certificate of Analysis Feb 24, 2023 U406318
B2318235 Certificate of Analysis Feb 24, 2023 U406318
J22111261 Certificate of Analysis Aug 03, 2022 U406318
J22111276 Certificate of Analysis Aug 03, 2022 U406318

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Chemical and Physical Properties

Sensitivity Moisture & Light sensitive
Melt Point(°C) >140°C
Molecular Weight 550.090 g/mol
XLogP3
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 15
Rotatable Bond Count 8
Exact Mass 549.914 Da
Monoisotopic Mass 549.914 Da
Topological Polar Surface Area 267.000 Ų
Heavy Atom Count 32
Formal Charge 0
Complexity 820.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 4

Alternative Products

  1. Uridine 5′-triphosphate trisodium salt hydrate
    Uridine 5′-triphosphate trisodium salt hydrate
    • ≥99%

    Starting at $19.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Ying Ding, Qingyan Jia, Yongmei Wen, Weimin Liu, Jiechao Ge, Jiasheng Wu, Hongyan Zhang, Pengfei Wang.  (2018)  New detection method for nucleoside triphosphates based on carbon dots: The distance-dependent singlet oxygen trapping.  ANALYTICA CHIMICA ACTA,  1031  (145). 

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