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Uridine 5′-triphosphate tris salt - ≥90%, high purity , CAS No.108321-53-5

    Grade & Purity:
  • ≥90%
In stock
Item Number
U338891
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SKU Size
Availability
Price Qty
U338891-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$128.90
U338891-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$508.90

a P2Y receptor agonist

View related series
Metabolite (5307)

Basic Description

Synonyms F85566 | uridine 5''-(tetrahydrogen triphosphate) | Uridine 5'-(tetrahydrogen triphosphate) | C00075 | KBio1_000269 | BRN 0071520 | DTXSID0041147 | KBio3_002692 | [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydro
Specifications & Purity ≥90%
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Uridine 5′-triphosphate tris salt is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinase assays.

Associated Targets(Human)

P2RY2 Tclin P2Y purinoceptor 2 (19 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P2RY6 Tchem P2Y purinoceptor 6 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P2RY11 Tchem P2Y purinoceptor 11 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P2RY4 Tchem P2Y purinoceptor 4 (10 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P2RY6 Tchem Pyrimidinergic receptor P2Y6 (717 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P2RY4 Tchem Pyrimidinergic receptor P2Y4 (598 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P2RY1 Tchem Purinergic receptor P2Y1 (1327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P2RY11 Tchem Purinergic receptor P2Y11 (134 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CAD Tchem Dihydroorotase (27 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P2RY2 Tclin Purinergic receptor P2Y2 (1109 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor (291 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLRMT Tbio DNA-directed RNA polymerase, mitochondrial (57 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Ggta1 N-acetyllactosaminide alpha-1,3-galactosyltransferase (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NS5B Hepatitis C virus NS5B RNA-dependent RNA polymerase (3026 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
B4GALT1 Beta-1,4-galactosyltransferase 1 (61 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Smiles C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
WGK Germany 3
PubChem CID 6133
Molecular Weight 484.14

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 484.140 g/mol
XLogP3 -5.800
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 15
Rotatable Bond Count 8
Exact Mass 483.969 Da
Monoisotopic Mass 483.969 Da
Topological Polar Surface Area 259.000 Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 839.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,    (1-7). 
2. Yao Yuying, Wang Yeru, Zhu Jingru, Guo Zhiqiang, Li Zongqiang, Li Qianru, Liu Su, Wang Yu, Yu Jinghua, Huang Jiadong.  (2023)  A spatially-controlled DNA triangular prism nanomachine for AND-gated intracellular imaging of ATP in acidic microenvironment.  MICROCHIMICA ACTA,  190  (11): (1-9). 
3. Xiaomeng Zhou, Saijin Huang, Dan Zhang, Wenfeng Liu, Wenxing Gao, Yumeng Xue, Li Shang.  (2023)  Gold Nanocluster-Based Fluorescent Microneedle Platform toward Visual Detection of ATP.  ANALYTICAL CHEMISTRY,  95  (32): (12104–12112). 
4. Ting Zeng, Jie Yin, Ziwen Liu, Zhaoxing Li, Yu Zhang, Yang Lv, Mei-Ling Lu, Min Luo, Meirong Chen, Yibei Xiao.  (2023)  Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system.  Cell Reports,  42  (112698). 
5. Xiaojuan Wang, Zefeng Mao, Ruipeng Chen, Shuning Li, Shuyue Ren, Jun Liang, Zhixian Gao.  (2022)  Self-assembled DNA origami-based duplexed aptasensors combined with centrifugal filters for efficient and rechargeable ATP detection.  BIOSENSORS & BIOELECTRONICS,  211  (114336). 
6. Jie Wei, Yumeng Li, Qingyang Si, Qiao Xiao, Qingmin Chen, Tianhui Jiao, Quansheng Chen, Xiaomei Chen.  (2022)  Hemin/G-quadruplex based electrochemical sensor for highly sensitive detection of ATP in fish.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  916  (116374). 
7. Xinran Shi, Liang Ji, Yuanyuan Hu, Jinyu Gu, Liming Wang, Wenwen Lu, Jiali Meng, Yan Du, Lingzhong Huang, Dongxia Nie, Yanyan Yu.  (2022)  Dual-responsive zeolitic imidazolate framework-90 for the combined detection and intracellular imaging of ATP and ROS.  SENSORS AND ACTUATORS B-CHEMICAL,  363  (131848). 
8. Xianfeng Wang, Xiaolong Chen, Chengxiang Chu, Yuanyi Deng, Mei Yang, Zhong Ji, Faliang Xu, Danqun Huo, Yang Luo, Changjun Hou.  (2020)  Four-stage signal amplification for trace ATP detection using allosteric probe-conjugated strand displacement and CRISPR/Cpf1 trans-cleavage (ASD-Cpf1).  SENSORS AND ACTUATORS B-CHEMICAL,  323  (128653). 
9. Wei Wang, Xin Li, Kai Tang, Zhiling Song, Xiliang Luo.  (2020)  A AuNP-capped cage fluorescent biosensor based on controlled-release and cyclic enzymatic amplification for ultrasensitive detection of ATP.  Journal of Materials Chemistry B,  (27): (5945-5951). 
10. Sun Chao, Zhao Shiyu, Qu Fei, Han Wenli, You Jinmao.  (2020)  Determination of adenosine triphosphate based on the use of fluorescent terbium(III) organic frameworks and aptamer modified gold nanoparticles.  MICROCHIMICA ACTA,  187  (1): (1-9). 
11. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,  171  (107698). 
12. Liwei Yang, Xiaoqiang Liu, Lele Li, Si Zhang, Hejie Zheng, Yunfei Tang, Huangxian Ju.  (2019)  A visible light photoelectrochemical sandwich aptasensor for adenosine triphosphate based on MgIn2S4-TiO2 nanoarray heterojunction.  BIOSENSORS & BIOELECTRONICS,  142  (111487). 
13. Shicai Xu, Chao Zhang, Shouzhen Jiang, Guodong Hu, Xiaoyue Li, Yan Zou, Hanping Liu, Jun Li, Zhenhua Li, Xiaoxin Wang, Mingzhen Li, Jihua Wang.  (2019)  Graphene foam field-effect transistor for ultra-sensitive label-free detection of ATP.  SENSORS AND ACTUATORS B-CHEMICAL,  284  (125). 
14. Qu Fei, Sun Chao, Lv Xiaoxia, You Jinmao.  (2018)  A terbium-based metal-organic framework@gold nanoparticle system as a fluorometric probe for aptamer based determination of adenosine triphosphate.  MICROCHIMICA ACTA,  185  (8): (1-8). 
15. Fei Qu, Jingwen Li, Wenli Han, Lian Xia, Jinmao You.  (2018)  Simultaneous Detection of Adenosine Triphosphate and Glucose Based on the Cu-Fenton Reaction.  SENSORS,  18  (7): (2151). 
16. Qu Fei, Mao Beibei, Xue Fangfang, Xia Lian, You Jinmao, Song Cuihua.  (2018)  Photoinduced electron transfer from polymer-templated Ag nanoclusters to G-quadruplex-hemin complexes for the construction of versatile biosensors and logic gate applications.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  410  (8): (2211-2219). 
17. Cheng Xia, Cen Yao, Xu Guanhong, Wei Fangdi, Shi Menglan, Xu Xiaoman, Sohail Muhammad, Hu Qin.  (2018)  Aptamer based fluorometric determination of ATP by exploiting the FRET between carbon dots and graphene oxide.  MICROCHIMICA ACTA,  185  (2): (1-8). 
18. Fangfang Li, Xuan Hu, Fengyi Wang, Baozhan Zheng, Juan Du, Dan Xiao.  (2018)  A fluorescent “on-off-on” probe for sensitive detection of ATP based on ATP displacing DNA from nanoceria.  TALANTA,  179  (285). 
19. Yong-Ping Dong, Ying Zhou, Jiao Wang, Jun-Jie Zhu.  (2016)  Electrogenerated Chemiluminescence Resonance Energy Transfer between Ru(bpy)32+ Electrogenerated Chemiluminescence and Gold Nanoparticles/Graphene Oxide Nanocomposites with Graphene Oxide as Coreactant and Its Sensing Application.  ANALYTICAL CHEMISTRY,  88  (10): (5469–5475). 
20. Ying Zhu, Xiao-chun Hu, Shuo Shi, Ru-ru Gao, Hai-liang Huang, Yan-yan Zhu, Xiao-yan Lv, Tian-ming Yao.  (2016)  Ultrasensitive and universal fluorescent aptasensor for the detection of biomolecules (ATP, adenosine and thrombin) based on DNA/Ag nanoclusters fluorescence light-up system.  BIOSENSORS & BIOELECTRONICS,  79  (205). 
21. Qingkun Kong, Meng Li, Chao Ma, Hongmei Yang, Shenguang Ge, Mei Yan, Jinghua Yu.  (2015)  Ultrasensitive electrochemiluminescence aptasensor based on a graphene/polyaniline composite film modified electrode and CdS quantum dot coated platinum nanostructured networks as labels.  RSC Advances,  (86): (70345-70351). 
22. Weiyan Liu, Hongmei Yang, Shenguang Ge, Lei Shen, Jinghua Yu, Mei Yan, Jiadong Huang.  (2015)  Application of bimetallic PtPd alloy decorated graphene in peroxydisulfate electrochemiluminescence aptasensor based on Ag dendrites decorated indium tin oxide device.  SENSORS AND ACTUATORS B-CHEMICAL,  209  (32). 
23. Meng Li, Hongmei Yang, Chao Ma, Yan Zhang, Shenguang Ge, Jinghua Yu, Mei Yan.  (2014)  A sensitive signal-off aptasensor for adenosine triphosphate based on the quenching of Ru(bpy)32+-doped silica nanoparticles electrochemiluminescence by ferrocene.  SENSORS AND ACTUATORS B-CHEMICAL,  191  (377). 
24. Juanjuan Lu, Mei Yan, Lei Ge, Shenguang Ge, Shaowei Wang, Jixian Yan, Jinghua Yu.  (2013)  Electrochemiluminescence of blue-luminescent graphene quantum dots and its application in ultrasensitive aptasensor for adenosine triphosphate detection.  BIOSENSORS & BIOELECTRONICS,  47  (271). 
25. Yuqing Zhang, Chunli Yang, Jiayang He, Zhihan Zhang, Yaqin Chai, Ruo Yuan, Wenju Xu.  (2025)  Dynamic switching circuit modulated by intramolecular conformation transition of DNA translator for versatile fluorescence biosensors.  BIOSENSORS & BIOELECTRONICS,    (117404). 
26. Hong Huang, Huiru Li, Yong Zhang, Xuhan Xia, Ningwen Zhang, Haixin Fan, Longhua Guo, Yongyong Cao, Hu Pan, Ruijie Deng, Yangang Wang, Rodrigo Ledesma-Amaro, Jianguo Xu.  (2025)  Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two-Photon Fluorescent Probe.  Advanced Science,    (2413220). 

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