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UNC669 - 10mM in DMSO, high purity , CAS No.1314241-44-5
Selective, competitive L3MBTL antagonist
Basic Description
Synonyms
1314241-44-5 | UNC669 | UNC 669 | (5-bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone | UNC-669 | (5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | CHEMBL1235119 | 3-Bromo-5-[(4-Pyrrolidin-1-Ylpiperidin-1-Yl)carbonyl]pyridine | C15H20BrN3O |
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Selective, competitive L3MBTL antagonist (IC 50 = 5 µM). Inhibits L3MBTL induced transcription repression. Active in vitro .
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Store at +4°C. The product can be stored for up to 12 months.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organoheterocyclic compounds
Class
Pyridines and derivatives
Subclass
Pyridinecarboxylic acids and derivatives
Intermediate Tree Nodes
Not available
Direct Parent
Pyridinecarboxylic acids and derivatives
Alternative Parents
N-acylpiperidines Aminopiperidines N-alkylpyrrolidines Aryl bromides Tertiary carboxylic acid amides Heteroaromatic compounds Trialkylamines Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organobromides Organic oxides Hydrocarbon derivatives
Molecular Framework
Aromatic heteromonocyclic compounds
Substituents
N-acyl-piperidine - Pyridine carboxylic acid or derivatives - 4-aminopiperidine - Aryl bromide - Aryl halide - Piperidine - N-alkylpyrrolidine - Heteroaromatic compound - Pyrrolidine - Tertiary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Tertiary aliphatic amine - Tertiary amine - Carboxylic acid derivative - Azacycle - Organooxygen compound - Organonitrogen compound - Organobromide - Organohalogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Amine - Organic nitrogen compound - Organopnictogen compound - Aromatic heteromonocyclic compound
Description
This compound belongs to the class of organic compounds known as pyridinecarboxylic acids and derivatives. These are compounds containing a pyridine ring bearing a carboxylic acid group or a derivative thereof.
External Descriptors
Not available
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
(5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
INCHI
InChI=1S/C15H20BrN3O/c16-13-9-12(10-17-11-13)15(20)19-7-3-14(4-8-19)18-5-1-2-6-18/h9-11,14H,1-8H2
InChIKey
CQERVFFAOOUFEQ-UHFFFAOYSA-N
Smiles
C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CN=C3)Br
Isomeric SMILES
C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CN=C3)Br
PubChem CID
46931242
Molecular Weight
338.24
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Molecular Weight
338.240 g/mol
XLogP3
2.100
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
337.079 Da
Monoisotopic Mass
337.079 Da
Topological Polar Surface Area
36.400 Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
338.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
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