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UNC0064-12 (VEGFR-2-IN-5) - 98%, high purity , CAS No.1430089-64-7

COA

Grade & Purity:

≥98%

Cas Number: 1430089-64-7
Molecular Weight: 364.45
PubChem CID: 90369695

In stock

Item Number

U412241

Grouped product items
SKU	Size	Availability	Price
U412241-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90
U412241-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$129.90
U412241-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$249.90
U412241-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90

View related series

Protein Tyrosine Kinase/RTK (1314) Receptor Tyrosine Kinase (1260) VEGFR (187) VEGFR2 inhibitor (1)

Basic Description

Synonyms	2,4-Pyrimidinediamine with linker \| 2, 4-Pyrimidinediamine with linker
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	UNC0064-12 (VEGFR-2-IN-5) is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 71.UNC0064-12 (VEGFR-2-IN-5) is a multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information UNC0064-12 (VEGFR-2-IN-5) is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 71.UNC0064-12 (VEGFR-2-IN-5) is a multikinase inhibitor and has a -NH2 terminal linker for further synthesis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Class Organonitrogen compounds
    - Subclass Amines
      - Level5 Aralkylamines
        Level6 Phenylalkylamines

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Class	Organonitrogen compounds
Subclass	Amines
Intermediate Tree Nodes	Aralkylamines
Direct Parent	Phenylalkylamines
Alternative Parents	Aniline and substituted anilines Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Pyrazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenylalkylamine - Aniline or substituted anilines - Secondary aliphatic/aromatic amine - Aminopyrimidine - Imidolactam - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Pyrazole - Azole - Azacycle - Organoheterocyclic compound - Secondary amine - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary aliphatic amine - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenylalkylamines. These are organic amines where the amine group is secondary and linked on one end to a phenyl group and on the other end, to an alkyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	2-N-[4-(3-aminopropylamino)phenyl]-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
INCHI	InChI=1S/C19H24N8/c20-9-1-10-21-14-4-6-15(7-5-14)23-19-22-11-8-17(25-19)24-18-12-16(26-27-18)13-2-3-13/h4-8,11-13,21H,1-3,9-10,20H2,(H3,22,23,24,25,26,27)
InChIKey	UYYZTTPXKIYERF-UHFFFAOYSA-N
Smiles	C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC=C(C=C4)NCCCN
Isomeric SMILES	C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC=C(C=C4)NCCCN
PubChem CID	90369695
Molecular Weight	364.45

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
G2417490	Certificate of Analysis	Apr 03, 2024	U412241
G2417491	Certificate of Analysis	Apr 03, 2024	U412241
G2417492	Certificate of Analysis	Apr 03, 2024	U412241
G2417493	Certificate of Analysis	Apr 03, 2024	U412241
G2417494	Certificate of Analysis	Apr 03, 2024	U412241
G2417495	Certificate of Analysis	Apr 03, 2024	U412241
G2417496	Certificate of Analysis	Apr 03, 2024	U412241
G2417497	Certificate of Analysis	Apr 03, 2024	U412241

Chemical and Physical Properties

Molecular Weight	364.400 g/mol
XLogP3	3.100
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	364.212 Da
Monoisotopic Mass	364.212 Da
Topological Polar Surface Area	117.000 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	437.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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