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UDP-G - 10mM in DMSO, high purity , CAS No.28053-08-9

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
U422983
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U422983-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$182.90

Highly potent P2Y 14 agonist

Basic Description

Synonyms 28053-08-9 | UDPG sodium salt | Uridine(5')disodiodiphospho(1)-alpha-D-glucose | Uridine 5'-diphosphoglucose disodium | UYD77NZ2JQ | Uridine 5'-diphosphoglucose disodium salt | disodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxid
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Highly potent, endogenous P2Y 14 agonist (EC 50 = 82 nM). Involved in modulation of gastric function. UDP also available .
Storage Temp Store at -80°C
Shipped In
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This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Pyrimidine nucleotides
Subclass Pyrimidine nucleotide sugars
Intermediate Tree Nodes Not available
Direct Parent Pyrimidine nucleotide sugars
Alternative Parents Pyrimidine ribonucleoside diphosphates  Pentose phosphates  Glycosylamines  Monosaccharide phosphates  Organic pyrophosphates  Pyrimidones  Alkyl phosphates  Hydropyrimidines  Oxanes  Vinylogous amides  Tetrahydrofurans  Heteroaromatic compounds  Ureas  Secondary alcohols  Lactams  Oxacyclic compounds  Azacyclic compounds  Polyols  Organic oxides  Hydrocarbon derivatives  Primary alcohols  Organopnictogen compounds  Organic sodium salts  Organonitrogen compounds  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyrimidine nucleotide sugar - Pyrimidine ribonucleoside diphosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Monosaccharide phosphate - Organic pyrophosphate - Pyrimidone - Hydropyrimidine - Monosaccharide - Organic phosphoric acid derivative - Oxane - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Vinylogous amide - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Lactam - Urea - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Oxacycle - Polyol - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic sodium salt - Primary alcohol - Hydrocarbon derivative - Organic oxygen compound - Organopnictogen compound - Organic oxide - Organic salt - Alcohol - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidine nucleotide sugars. These are pyrimidine nucleotides bound to a saccharide derivative through the terminal phosphate group.
External Descriptors Not available

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CSNK1D Tchem Casein kinase I delta (4546 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
S1PR1 Tclin Sphingosine 1-phosphate receptor Edg-1 (5806 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
C5AR1 Tclin C5a anaphylatoxin chemotactic receptor (2677 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U2OS (164939 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CX3CR1 Tchem C-X3-C chemokine receptor 1 (1686 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FPR2 Tchem Lipoxin A4 receptor (3472 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GPR35 Tchem G-protein coupled receptor 35 (2643 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TRIM24 Tchem Transcription intermediary factor 1-alpha (2087 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRPF1 Tchem Peregrin (2217 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK-293T (167025 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Aplnr Apelin receptor (201 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Gpr119 Glucose-dependent insulinotropic receptor (270 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name disodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate
INCHI InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1
InChIKey PKJQEQVCYGYYMM-QBNUFUENSA-L
Smiles C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OC3C(C(C(C(O3)CO)O)O)O)O)O.[Na+].[Na+]
Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O.[Na+].[Na+]
Alternate CAS 117756-22-6
PubChem CID 119803
Molecular Weight 610.27

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 610.270 g/mol
XLogP3
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 17
Rotatable Bond Count 9
Exact Mass 610.019 Da
Monoisotopic Mass 610.019 Da
Topological Polar Surface Area 297.000 Ų
Heavy Atom Count 38
Formal Charge 0
Complexity 948.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 9
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 3

Citations of This Product

1. Xuqiu He, Ronghao Huang, Lipeng Liu, Yingying Li, Wenzhao Wang, Qingshan Xu, Youben Yu, Tianshan Zhou.  (2021)  CsUGT78A15 catalyzes the anthocyanidin 3-O-galactoside biosynthesis in tea plants.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,  166  (738). 
2. Cao Shiyang, Wang Tong, Ren Yifan, Wu Gengshan, Zhang Yuan, Tan Yafang, Zhou Yazhou, Chen Hongyan, Zhang Yu, Song Yajun, Yang Ruifu, Du Zongmin.  (2024)  A protein O-GlcNAc glycosyltransferase regulates the antioxidative response in Yersinia pestis.  Nature Communications,  15  (1): (1-16). 
3. Lin Ge, Yu Xia, Wenxin Xu, Ruobing Jia, Tingting Zhang.  (2025)  Efficient Biosynthesis of Gastrodin by UDP-Glycosyltransferase from Rauvolfia serpentina.  JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,  35  (e2501002). 
4. Yang Gu, Yaru Jiang, Changfan Li, Jiang Zhu, Xueyao Lu, Jianyue Ge, Mengchen Hu, Jieying Deng, Jingbo Ma, Zhiliang Yang, Xiaoman Sun, Feng Xue, Guocheng Du, Peng Xu, He Huang.  (2024)  High titer production of gastrodin enabled by systematic refactoring of yeast genome and an antisense-transcriptional regulation toolkit.  METABOLIC ENGINEERING,  82  (250). 
5. Xiaomeng Zhang, Xinquan Tian, Junyu Luo, Xiaoyang Wang, Shoupu He, Gaofei Sun, Ruidan Dong, Panhong Dai, Xiao Wang, Zhaoe Pan, Baojun Chen, Daowu Hu, Liru Wang, Baoyin Pang, Aishuang Xing, Guoyong Fu, Baoquan Wang, Jinjie Cui, Lei Ma, Xiongming Du.  (2025)  Identification of UDP-glucosyltransferase involved in the biosynthesis of phloridzin in Gossypium hirsutum.  PLANT JOURNAL,  121  (3): (e17248). 

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