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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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T128536-25KU
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25KU |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$194.90
|
|
|
T128536-100KU
|
100KU |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$539.90
|
|
| Product Name | Tyrosinase from mushroom, CAS No.9002-10-2 |
|---|---|
| Synonyms | Polyphenol Oxidase | Catechol Oxidase | Monophenol Monooxygenase | Monophenol | dihydroxyphenylalanine:oxygen oxidoreductase |
| Grade | EnzymoPure™ |
| Product Description |
Inhibitors Calculation
|
| Specifications & Purity | EnzymoPure™, ≥500 units/mg dry weight |
| Biochemical and Physiological Mechanisms | Converts tyrosine to L-DOPA or tyramine to dopamine. |
| Concentration | ≥500 units/mg dry weight |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| CAS | 9002-10-2 |
| Enzyme Commission Number | I.U.B.: 1.14.18.1 |
| Unit definition | Unit Definition: One unit causes an increase in the absorbance at 280 nm of 0.001 per minute at 25°C, pH 6.5, using L-tyrosine as substrate. |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 27, 2025 | T128536 | |
| Certificate of Analysis | Feb 27, 2025 | T128536 | |
| Certificate of Analysis | Nov 28, 2024 | T128536 | |
| Certificate of Analysis | Nov 28, 2024 | T128536 | |
| Certificate of Analysis | Oct 22, 2024 | T128536 | |
| Certificate of Analysis | Oct 22, 2024 | T128536 | |
| Certificate of Analysis | Jul 09, 2024 | T128536 | |
| Certificate of Analysis | Jul 09, 2024 | T128536 | |
| Certificate of Analysis | Jul 09, 2024 | T128536 | |
| Certificate of Analysis | May 22, 2024 | T128536 | |
| Certificate of Analysis | May 22, 2024 | T128536 | |
| Certificate of Analysis | Nov 21, 2023 | T128536 | |
| Certificate of Analysis | Nov 21, 2023 | T128536 | |
| Certificate of Analysis | Aug 15, 2023 | T128536 | |
| Certificate of Analysis | Aug 15, 2023 | T128536 | |
| Certificate of Analysis | Oct 14, 2022 | T128536 | |
| Certificate of Analysis | Oct 14, 2022 | T128536 | |
| Certificate of Analysis | Dec 14, 2021 | T128536 | |
| Certificate of Analysis | Apr 30, 2021 | T128536 |
Starting at $609.90
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| 2. Jinpeng Lv, Ximei Zhang, Xiaohong An, Yan Cao, Duo Meng, Kun Zou, Rongyin Gao, Ruzhi Zhang. (2024) The inhibition of VDAC1 oligomerization promotes pigmentation through the CaMK–CRTCs/CREB–MITF pathway. EXPERIMENTAL CELL RESEARCH, 434 (113874). |
| 3. Muhammad Aurang Zeb, Peng-Yun Yang, De-Wen Bi, Wen-Chao Tu, Xiao-Li Li, Rui-Han Zhang, Xing-Jie Zhang, Wei-Lie Xiao. (2023) Chemical constituents from Vitex negundo var. cannabifolia (Sieb. et Zucc.) Hand.-Mazz. (Lamiaceae) and their chemotaxonomic significance. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 111 (104719). |
| 4. Jianjin GUO, Lu BAI, Chi-Tang HO, Sen GUO, Naisheng BAI. (2023) Chemical characterization, multivariate analysis and in vitro bioactivity evaluation of the roots of Fraxinus mandshurica. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 51 (100303). |
| 5. Hong Wang, Mengmeng Gu, Menghua Yan, Xiuming Wu, Yuming Dong, Guang-Li Wang. (2023) Catechol exerts an in situ surface oxygen vacancy effect on BiOI: an innovative signal transduction mode for cathodic photoelectrochemistry. Journal of Materials Chemistry B, 11 (23): (5123-5130). |
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| 8. Hong Liu, Xuliang Yang, Bo Huang, Hongxiang Liu. (2023) A universal approach for synthesis of copper nanoclusters templated by G-rich oligonucleotide sequences and their applications in sensing. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 297 (122740). |
| 9. Kanglin Pei, Di Li, Wenjing Qi, Di Wu. (2023) Ultrarapid Microwave-Assisted Synthesis of Fluorescent Silver Coordination Polymer Nanoparticles and Its Application in Detecting Alkaline Phosphatase Activity. MOLECULES, 28 (4): (1892). |
| 10. Qin-Tao Zhou, Peng-Yun Yang, Quan-Yu Yang, Wen-Hui Pang, Xiao-Li Li, Xing-Jie Zhang, Rui-Han Zhang, Wei-Lie Xiao. (2023) Chemical Constituents of the Branches and Leaves of Picrasma chinensis P.Y. Chen and Tyrosinase Inhibiting Activity. CHEMISTRY & BIODIVERSITY, 20 (3): (e202201171). |
| 11. Wang Wenxian, Yang Dan, Zhou Yufei, Zhang Yuding, Guan Lijiao, Zhang Xianfen, Xue Weiming, Huang Saipeng. (2023) Novel Green Fluorescent Probe Stem From Carbon Quantum Dots for Specific Recognition of Tyrosinase in Serum and Living Cells. JOURNAL OF FLUORESCENCE, 33 (2): (739-750). |
| 12. Sun Tingwei, Guo Qingquan, Wu Shaojuan, Su Kui, Lun Jingwen, Zhang Yihan, Tan Wen, Zhao Haishan. (2022) Comparative Study of High-throughput Screening Models for Anti-hyperpigmentation Compounds. BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 65 (e22210281). |
| 13. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu. (2022) Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system. Analytical Methods, 14 (37): (3632-3637). |
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| 21. Can Chen, Guotong Ruan, Yujie Sun, Lili Wang, Chengwu Zhang, Jinhua Liu. (2021) In situ Cu2+-triggered wavelength-tunable fluorescent sensor for highly sensitive sensing inorganic pyrophosphatase activity and its logic gate application. SENSORS AND ACTUATORS B-CHEMICAL, 346 (130439). |
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| 26. Congcong Yu, Qingpeng Cao, Tingting Tu, Yu Cai, Lu Fang, Xuesong Ye, Bo Liang. (2020) Differential coulometry based on dual screen-printed strips for high accuracy levodopa determination towards Parkinson's disease management. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 190 (113498). |
| 27. Huang Xuemin, Zhao Huanan, Qiu Wen, Wang Jian, Guo Longhua, Lin Zhenyu, Pan Wei, Wu Yong, Qiu Bin. (2020) A fluorescence signal amplification strategy for modification-free ratiometric determination of tyrosinase in situ based on the use of dual-templated copper nanoclusters. MICROCHIMICA ACTA, 187 (4): (1-9). |
| 28. Can Chen, Fenghua Geng, Yongxiang Wang, Haidong Yu, Lin Li, Sheng Yang, Jinhua Liu, Wei Huang. (2019) Design of a nanoswitch for sequentially multi-species assay based on competitive interaction between DNA-templated fluorescent copper nanoparticles, Cr3+ and pyrophosphate and ALP. TALANTA, 205 (120132). |
| 29. Wang Dongwei, Wang Peng, Liu Donghui, Zhou Zhiqiang. (2019) Fluorometric atrazine assay based on the use of nitrogen-doped graphene quantum dots and on inhibition of the activity of tyrosinase. MICROCHIMICA ACTA, 186 (8): (1-7). |
| 30. Yunqing Wu, Yuxin Chen, Shiqin Zhang, Lizhi Zhang, Jingming Gong. (2019) Bifunctional S, N-Codoped carbon dots-based novel electrochemiluminescent bioassay for ultrasensitive detection of atrazine using activated mesoporous biocarbon as enzyme nanocarriers. ANALYTICA CHIMICA ACTA, 1073 (45). |
| 31. Dong-Mei Liu, Jun-Li Yang, Wei Ha, Juan Chen, Yan-Ping Shi. (2017) Kinetics and inhibition study of tyrosinase by pressure mediated microanalysis. ANALYTICAL BIOCHEMISTRY, 525 (54). |
| 32. Huihui Wang,Yunyun Lu,Lun Wang,Hongqi Chen. (2019-02-18) Detection of tyramine and tyrosinase activity using red region emission NaGdF4:Yb,Er@NaYF4 upconversion nanoparticles.. Talanta, 197 (558-566). |
| 33. Zhenyuan Wang, Tie Dong, Jin Yang, Yiyu Wang, Mi Wang, Jiaheng Zhang. (2025) A supramolecular tranexamic acid with enhanced permeability and bioactivity. Journal of Materials Chemistry B, |
| 34. Yuhe Shen, Rongxin Su, Hatice Altug, Zekai Liu, Xuelin Zhang, Xiaojian Xu, Yaoyu Liang, Jia Kong, Qing Li, Yuefei Wang, Wei Qi. (2024) Bioinspired Three-Component System to Prepare Full-Color Functional Biomimetic Pigments. ACS Applied Materials & Interfaces, 16 (31): (40531-40542). |
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| 44. Xiaohong Yu, Mengli Peng, Xiaocheng Liu, Yueling Shang, Dujun Wang, Wenbin Jin, Fengwei Li. (2024) Physicochemical properties, moisture retention, and biological activities of polysaccharides from Panax notoginseng separated by fractional precipitation. CHEMISTRY & BIODIVERSITY, (e202402002). |
| 45. Yan-Xia Li, He Ma, Le Shi, Zhong-Fei Zhang, Yu-Meng Wu, Chao Yan, Yan Chen, Yong-Ming Lu. (2025) Purification, characterization and protective effects on UVB-induced photoaging in zebrafish of Pleurotus citrinopileatus polysaccharide PCP-2. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, |
| 46. Shi-Huan Guo, Zimeng Zhang, Xi Zuo, Sitong Jiao, Jingyao Sun, Yahao Yang, Yahong Yuan, Tianli Yue. (2025) Synthesis and evaluation of the antioxidant, anti-tyrosinase and anti-browning activities of N-caffeoyl amino acid methyl esters. LWT-FOOD SCIENCE AND TECHNOLOGY, 217 (117409). |
| 47. Zuhua Zeng, Ying Tan, Tiantian Luo, Zhengwei Li, Guihao Hu, Yao Liu, Ling He, Haiyu Wang, Lei Zhong, Haiying Wang, Tianwei Liu, Jiang Zhu. (2025) Tyrosinase-Activated MRI and PET Probes for Selective Melanoma Imaging. ACS Sensors, |