Basic Description

Synonyms	s3162 \| TYLOSIN TARTRATE [USP MONOGRAPH] \| Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) \| Tylosin tartrate (USP) \| Tylosin (tartrate) \| NSC 758961 \| Tylan injectable \| EINECS 215-781-5 \| DTXSID3045938 \| Tylosin tartrate, potency: >=800 units/mg tylosi
Specifications & Purity	BioReagent, for cell culture, 0.1 μm filtered, 8 mg/mL in 0.9% NaCl
Biochemical and Physiological Mechanisms	Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and M
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	BioReagent, for cell culture
Product Description	General Description Chemical structure: macrolide Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L. Application Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation. Other Notes Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Carbohydrates and carbohydrate conjugates
      - Level5 Aminosaccharides
        Level6 Aminoglycosides

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes	Aminosaccharides
Direct Parent	Aminoglycosides
Alternative Parents	Macrolides and analogues Disaccharides O-glycosyl compounds Short-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Sugar acids and derivatives Oxanes Alpha hydroxy acids and derivatives Fatty acids and conjugates Dicarboxylic acids and derivatives Alpha-hydrogen aldehydes Tertiary alcohols Secondary alcohols 1,2-aminoalcohols Cyclic ketones Trialkylamines Lactones Amino acids and derivatives Carboxylic acid esters Oxacyclic compounds Acetals Dialkyl ethers Carboxylic acids Hydrocarbon derivatives Organopnictogen compounds Organic oxides
Molecular Framework	Not available
Substituents	Aminoglycoside core - Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Beta-hydroxy acid - Short-chain hydroxy acid - Sugar acid - Alpha-hydroxy acid - Dicarboxylic acid or derivatives - Hydroxy acid - Fatty acid - Oxane - Tertiary alcohol - Alpha-hydrogen aldehyde - Secondary alcohol - Tertiary aliphatic amine - Tertiary amine - Cyclic ketone - Lactone - Ketone - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Oxacycle - Organoheterocyclic compound - Ether - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Acetal - Organic nitrogen compound - Aldehyde - Amine - Organopnictogen compound - Carbonyl group - Organic oxide - Organonitrogen compound - Alcohol - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(2R,3R)-2,3-dihydroxybutanedioic acid;2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
INCHI	InChI=1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
InChIKey	ICVKYYINQHWDLM-KBEWXLTPSA-N
Smiles	O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
Isomeric SMILES	CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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2 results found

Lot Number	Certificate Type	Date	Item
C2503442	Certificate of Analysis	Feb 14, 2025	T433510
H2323128	Certificate of Analysis	Aug 04, 2023	T433510

Chemical and Physical Properties

Molecular Weight	1066.200 g/mol
XLogP3
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	24
Rotatable Bond Count	16
Exact Mass	1065.54 Da
Monoisotopic Mass	1065.54 Da
Topological Polar Surface Area	354.000 Å²
Heavy Atom Count	74
Formal Charge	0
Complexity	1700.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	23
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	2
Covalently-Bonded Unit Count	2

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Bing Wang, Qingtong Cao, Ming Cheng, Guomin Li, Jian Zhang, Hong Jiang. (2023) Photocatalytic degradation of antibiotics in water by pollution-free photocatalytic films with a three-dimensional layered structure and the reaction mechanism study. Journal of Water Process Engineering, 52 (103550).
2. Zhiyan Huang, Tenglu Wang, Minxian Shen, Zhujian Huang, Yunxiao Chong, Lihua Cui. (2019) Coagulation treatment of swine wastewater by the method of in-situ forming layered double hydroxides and sludge recycling for preparation of biochar composite catalyst. CHEMICAL ENGINEERING JOURNAL, 369 (784).
3. Chan-Yuan YAO, Jin-Yi YANG, Zhen-Lin XU, Hong WANG, Hong-Tao LEI, Yuan-Ming SUN, Yuan-Xin TIAN, Yu-Dong SHEN. (2018) Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Tylosin in Milk and Water Samples. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 46 (1275).
4. Yuehong Song, Shanshan Song, Liqiang Liu, Hua Kuang, Lingling Guo, Chuanlai Xu. (2016) Simultaneous detection of tylosin and tilmicosin in honey using a novel immunoassay and immunochromatographic strip based on an innovative hapten. FOOD AND AGRICULTURAL IMMUNOLOGY, 27 (3): (314-328).

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Tylosin solution - 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture, high purity , CAS No.74610-55-2