Basic Description

Synonyms	(2E)-10-hydroxydec-2-enoic acid \| Q16908844 \| QHBZHVUGQROELI-SOFGYWHQSA-N \| Silotermo Carmine G \| trans-10-hydroxydec-2-enoic acid \| DS-18448 \| 10-Hydroxy-2-decylenic acid \| (E)-10-Hydroxy-2-decenoic acid \| AC-34577 \| DTXSID601045504 \| LMFA01050157 \| Quee
Specifications & Purity	≥97%(T)
Biochemical and Physiological Mechanisms	VEGF inhibitor. Inhibits VEGF-induced angiogenesis. Suppresses VEGF-induced endothelial cell proliferation and migration. Promotes neurogenesis. Shows antiangiogenic, antioxidant and DNA-protective effects in vivo. Orally active.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Hydroxy acids and derivatives
    - Subclass Medium-chain hydroxy acids and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Hydroxy acids and derivatives
Subclass	Medium-chain hydroxy acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Medium-chain hydroxy acids and derivatives
Alternative Parents	Medium-chain fatty acids Hydroxy fatty acids Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Medium-chain hydroxy acid - Medium-chain fatty acid - Hydroxy fatty acid - Straight chain fatty acid - Fatty acyl - Fatty acid - Unsaturated fatty acid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Carbonyl group - Organic oxide - Organic oxygen compound - Alcohol - Organooxygen compound - Primary alcohol - Hydrocarbon derivative - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as medium-chain hydroxy acids and derivatives. These are hydroxy acids with a 6 to 12 carbon atoms long side chain.
External Descriptors	Hydroxy fatty acids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504763565
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504763565
IUPAC Name	(E)-10-hydroxydec-2-enoic acid
INCHI	InChI=1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+
InChIKey	QHBZHVUGQROELI-SOFGYWHQSA-N
Smiles	C(CCCC=CC(=O)O)CCCO
Isomeric SMILES	C(CCC/C=C/C(=O)O)CCCO
Molecular Weight	186.25
Reaxy-Rn	1765264
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1765264&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number	Certificate Type	Date	Item
D1725039	Certificate of Analysis	Nov 07, 2024	H140068
G2431179	Certificate of Analysis	Jul 18, 2024	H140068
G2431182	Certificate of Analysis	Jul 18, 2024	H140068
G2431183	Certificate of Analysis	Jul 18, 2024	H140068
G2431181	Certificate of Analysis	Jul 18, 2024	H140068
G2431178	Certificate of Analysis	Jul 18, 2024	H140068
G2431180	Certificate of Analysis	Jul 18, 2024	H140068
A2409321	Certificate of Analysis	Dec 20, 2023	H140068
A2409322	Certificate of Analysis	Dec 20, 2023	H140068
A2409323	Certificate of Analysis	Dec 20, 2023	H140068
A2409324	Certificate of Analysis	Dec 20, 2023	H140068
A2409325	Certificate of Analysis	Dec 20, 2023	H140068
B2025084	Certificate of Analysis	Dec 18, 2023	H140068
J1512067	Certificate of Analysis	Jul 10, 2023	H140068
D1823062	Certificate of Analysis	Feb 23, 2022	H140068

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Chemical and Physical Properties

Sensitivity	Heat sensitive
Melt Point(°C)	64.0-68.0℃
Molecular Weight	186.250 g/mol
XLogP3	2.200
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	8
Exact Mass	186.126 Da
Monoisotopic Mass	186.126 Da
Topological Polar Surface Area	57.500 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	152.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shixuan Su, Shanshan Li, Jing Hu, Ting Yu, Lingchen Tao, Fuliang Hu, Yunlei Xianyu. (2022) A colorimetric sensing strategy for detecting 10-hydroxy-2-decenoic acid in royal jelly based on Ag(I)-tetramethylbenzidine. SENSORS AND ACTUATORS B-CHEMICAL, 354 (131241).
2. Shuai Zhuang, Huihui Ming, Wenjie Yu, Liping Luo. (2025) Identification of freshness and metabolite changes of royal jelly during storage using Nano-ESI-MS and UPLC-Q/TOF-MS. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 139 (107092).
3. Xinqi Huang, Lu Xiu, Yumei An, Yuan Gong, Sunao Li, Xueshi Chen, Chao Liu, Jianghuiwen Lu, Haiyan Shan, Jie Chang, Mingyang Zhang. (2024) Preventive Effect of Royal Jelly and 10-HDA on Skin Damage in Diabetic Mice through Regulating Keratinocyte Wnt/β-Catenin and Pyroptosis Pathway. MOLECULAR NUTRITION & FOOD RESEARCH, 68 (19): (2400098).

Solution Calculators

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SKU	Size	Availability	Price
H140068-250mg	250mg	3	$9.90
H140068-1g	1g	2	$12.90
H140068-5g	5g	1	$19.90
H140068-25g	25g	1	$63.90
H140068-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$179.90

trans-10-Hydroxy-2-decenoic Acid - ≥97.0%(T), high purity , CAS No.14113-05-4