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Thyroxine methyl ester - 95%, high purity , CAS No.32180-11-3

    Grade & Purity:
  • ≥95%
In stock
Item Number
T275997
Grouped product items
SKU Size
Availability
Price Qty
T275997-50mg
50mg
3
$56.90
T275997-250mg
250mg
3
$218.90
T275997-1g
1g
2
$786.90

Malate dehydrogenase inhibitor.

Basic Description

Synonyms (S)-Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate | SCHEMBL8369341 | Thyroxine Methyl Ester | (S)-Methyl2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate | ZTSGDCMQRKBJKC-ZDUSSCGKSA-N | L-Tyrosine, O-(4
Specifications & Purity ≥95%
Biochemical and Physiological Mechanisms Methyl ester analog of thyroxine. Malate dehydrogenase inhibitor.
Storage Temp Protected from light,Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.


application:

Thyroxine Methyl Ester is the methyl ester analog of Thyroxine (T425600) with high cross reactivity with thyroxine-specific monoclonal antibodies of humans and lab animals. It is an inhibitor of malate dehydrogenase.Thyroxine Methyl Ester is suitable for malate dehydrogenase (MDH) related research.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent Phenylalanine and derivatives
Alternative Parents Alpha amino acid esters  Diphenylethers  Diarylethers  Amphetamines and derivatives  Phenoxy compounds  Phenol ethers  O-iodophenols  Aralkylamines  Fatty acid esters  Iodobenzenes  Aryl iodides  Methyl esters  Monocarboxylic acids and derivatives  Hydrocarbon derivatives  Organoiodides  Organic oxides  Carbonyl compounds  Organopnictogen compounds  Monoalkylamines  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Phenylalanine or derivatives - Alpha-amino acid ester - Diphenylether - Diaryl ether - Amphetamine or derivatives - Phenoxy compound - 2-halophenol - 2-iodophenol - Phenol ether - Fatty acid ester - Halobenzene - Iodobenzene - Phenol - Aralkylamine - Fatty acyl - Aryl halide - Benzenoid - Aryl iodide - Monocyclic benzene moiety - Methyl ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Ether - Organic oxide - Amine - Organic nitrogen compound - Organonitrogen compound - Organopnictogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organohalogen compound - Primary amine - Organoiodide - Organic oxygen compound - Primary aliphatic amine - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as phenylalanine and derivatives. These are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Not available

Names and Identifiers

Pubchem Sid 504767530
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504767530
IUPAC Name methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
INCHI InChI=1S/C16H13I4NO4/c1-24-16(23)13(21)4-7-2-11(19)15(12(20)3-7)25-8-5-9(17)14(22)10(18)6-8/h2-3,5-6,13,22H,4,21H2,1H3/t13-/m0/s1
InChIKey ZTSGDCMQRKBJKC-ZDUSSCGKSA-N
Smiles COC(=O)C(CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)N
Isomeric SMILES COC(=O)[C@H](CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)N
PubChem CID 13911218
Molecular Weight 790.9

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number Certificate Type Date Item
L2214002 Certificate of Analysis Sep 21, 2023 T275997
G2201110 Certificate of Analysis Apr 14, 2023 T275997
F2230481 Certificate of Analysis Apr 14, 2023 T275997
F2230482 Certificate of Analysis Apr 14, 2023 T275997

Chemical and Physical Properties

Solubility Soluble in DMSO;Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Heated)
Sensitivity light sensitive
Melt Point(°C) 88-91°C
Molecular Weight 790.900 g/mol
XLogP3 5.000
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 6
Exact Mass 790.702 Da
Monoisotopic Mass 790.702 Da
Topological Polar Surface Area 81.800 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 434.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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