Basic Description

Synonyms	CS-W013418 \| AKOS008988060 \| RIIUAPMWDSRBSH-UHFFFAOYSA-N \| Thiodiglycolic anhydride, AldrichCPR \| DTXSID30186306 \| Thiodiglycolic anhydride \| FT-0634751 \| H10798 \| C4H4O3S \| 1-Oxa-4-thia-cyclohexan-2,6-dione \| 1,4-Oxathiane-2,6-dione # \| STR03033 \| MFCD00
Specifications & Purity	≥98%
Storage Temp	Argon charged
Shipped In	Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Oxathianes

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Oxathianes
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Oxathianes
Alternative Parents	Dicarboxylic acids and derivatives Carboxylic acid anhydrides Oxacyclic compounds Dialkylthioethers Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	1,4-oxathiane - Dicarboxylic acid or derivatives - Carboxylic acid anhydride - Oxacycle - Dialkylthioether - Thioether - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as oxathianes. These are compounds containing an oxathiane moiety, which consists of a saturated aliphatic six-member ring with one oxygen atom, a sulfur atom, and four carbon atoms. Isomers of oxaphospholane include 1,2-oxathiane, 1,3-oxathiane,and 1,4-oxathiane.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504757139
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504757139
IUPAC Name	1,4-oxathiane-2,6-dione
INCHI	InChI=1S/C4H4O3S/c5-3-1-8-2-4(6)7-3/h1-2H2
InChIKey	RIIUAPMWDSRBSH-UHFFFAOYSA-N
Smiles	C1C(=O)OC(=O)CS1
Isomeric SMILES	C1C(=O)OC(=O)CS1
PubChem CID	137871
Molecular Weight	132.13
Beilstein	112528

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
K2113389	Certificate of Analysis	May 15, 2025	T136548
K2113387	Certificate of Analysis	May 15, 2025	T136548
A2509086	Certificate of Analysis	Jan 16, 2025	T136548
A2509085	Certificate of Analysis	Jan 16, 2025	T136548
L2427144	Certificate of Analysis	Jan 04, 2025	T136548
A2510628	Certificate of Analysis	Jan 04, 2025	T136548
G1919264	Certificate of Analysis	Oct 07, 2023	T136548
K2113388	Certificate of Analysis	Aug 18, 2023	T136548
K2113390	Certificate of Analysis	Aug 18, 2023	T136548
K2218124	Certificate of Analysis	Nov 21, 2022	T136548

Chemical and Physical Properties

Sensitivity	Hygroscopic
Melt Point(°C)	95-100°
Molecular Weight	132.140 g/mol
XLogP3	0.400
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	131.988 Da
Monoisotopic Mass	131.988 Da
Topological Polar Surface Area	68.700 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	117.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jianpeng Qin, Meng Sun, Yanli Zhen, Ji Li, Dongkai Wang. (2023) A ROS-response hyaluronic acid-coated/chitosan polymer prodrug for enhanced tumour targeting efficacy of SN38. JOURNAL OF DRUG TARGETING, 31 (6): (623-633).
2. Haiting Xu, Linxin Dai, Wenbiao Nie, Ruifeng Luo, Xiulan Pu, Lingling Dong, Qiyan Chen, Shanshan Qi, Xiaoqin Han, Jieshu You, Jinming Zhang, Fei Gao. (2023) Oral cyclodextrin supramolecular for ulcerative colitis treatment through macrophages targeting / ROS response-based accurate on-demand drug release strategy. MATERIALS & DESIGN, 226 (111606).
3. Ruifeng Wu, Zhiqiang Zhang, Baohua Wang, Ge Chen, Yaozhong Zhang, Haowen Deng, Zilong Tang, Junjie Mao, Lei Wang. (2022) Combination Chemotherapy of Lung Cancer – Co-Delivery of Docetaxel Prodrug and Cisplatin Using Aptamer-Decorated Lipid–Polymer Hybrid Nanoparticles. Drug Design Development and Therapy,
4. Wenfeng Xue, Ronghao Liu, Xiaoxia Liu, Yangyang Wang, Ping Lv, Yanzhao Yang. (2022) Selective extraction of Nd(III) by novel carboxylic acid based ionic liquids without diluent from waste NdFeB magnets. JOURNAL OF MOLECULAR LIQUIDS, 364 (119919).
5. Hui Yan, Danping Wang, Chengyin Tian, Long Zhao, Yong Wang, Guoqing Long, Bingjun Sun, Jingming Jia, Anhua Wang. (2024) Elaboration a ROS-responsive darutigenol prodrug nanoassemblies for inflammatory arthritis treatment. Nano Today, 55 (102220).
6. Jiayu Guo, Xiaoxiao Zhang, Fudan Dong, Simeng Wang, Danping Wang, Yaqiao Li, Shiyi Zuo, Qing Wang, Wenxiao Li, Jin Sun, Zhonggui He, Tianhong Zhang, Qikun Jiang, Bingjun Sun. (2025) Revealing the impact of modified modules flexibility on gemcitabine prodrug nanoassemblies for effective cancer therapy. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 677 (941).

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SKU	Size	Availability	Price
T136548-1g	1g	3	$15.90
T136548-5g	5g	2	$58.90
T136548-10g	10g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90
T136548-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$227.90
T136548-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$714.90
T136548-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,214.90

Thiodiglycolic anhydride - 98%, high purity , CAS No.3261-87-8