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Thalidomide 4'-ether-alkylC2-amine hydrochloride - 98%, high purity , CAS No.2341840-99-9

COA

Grade & Purity:

≥98%

Cas Number: 2341840-99-9
Molecular Weight: 353.76
PubChem CID: 138991788
PubChem SID: 504773545

In stock

Item Number

T288723

Grouped product items
SKU	Size	Availability	Price
T288723-10mg	10mg	3	$78.90
T288723-25mg	25mg	1	$149.90
T288723-50mg	50mg	2	$238.90
T288723-100mg	100mg	2	$378.90

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

View related series

Aliphatic Linkers (102) Apoptosis (4276) Autophagy (1917) DOTA reagent (12) E3 Ligase Ligand-Linker Conjugates (88) Lipid PEG (395) PROTAC (2077) PROTAC linker (720)

Basic Description

Synonyms	Thalidomide - linker 6 \| 4-(2-Aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride \| Thalidomide-4-O-C2-NH2 hydrochloride
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Functionalized cereblon ligand for PROTAC®research and development; incorporates an E3 ligase ligand plus an alkylC2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

Pubchem Sid	504773545
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504773545
IUPAC Name	4-(2-aminoethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
INCHI	InChI=1S/C15H15N3O5.ClH/c16-6-7-23-10-3-1-2-8-12(10)15(22)18(14(8)21)9-4-5-11(19)17-13(9)20;/h1-3,9H,4-7,16H2,(H,17,19,20);1H
InChIKey	AZQNUQDFOMUSBB-UHFFFAOYSA-N
Smiles	C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCN.Cl
PubChem CID	138991788
Molecular Weight	353.76

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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5 results found

Lot Number	Certificate Type	Date	Item
K2323231	Certificate of Analysis	Nov 09, 2023	T288723
K2323232	Certificate of Analysis	Nov 09, 2023	T288723
K2323242	Certificate of Analysis	Nov 09, 2023	T288723
K2323243	Certificate of Analysis	Nov 09, 2023	T288723
K2323244	Certificate of Analysis	Nov 09, 2023	T288723

Chemical and Physical Properties

Sensitivity	Moisture sensitive
Molecular Weight	353.760 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	353.078 Da
Monoisotopic Mass	353.078 Da
Topological Polar Surface Area	119.000 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	549.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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