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TFLLR-NH₂, Agonist of PAR1, CAS No.rp175274, Agonist of PAR1

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rp175274
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rp175274-500μg
500μg
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$1,334.90
rp175274-1mg
1mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90
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PAR1 Agonist (3)

Basic Description

Product Name TFLLR-NH₂, Agonist of PAR1, CAS No.rp175274
Synonyms PEPTIDE1{T.F.L.L.R.[am]}$$$$;Thr-Phe-Leu-Leu-Arg-amide
Grade Moligand™
Specifications & Purity Moligand™
Action Type AGONIST
Mechanism of action Agonist of PAR1

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct Parent Oligopeptides
Alternative Parents Phenylalanine and derivatives  Leucine and derivatives  N-acyl-alpha amino acids and derivatives  Alpha amino acid amides  Amphetamines and derivatives  N-acyl amines  Secondary carboxylic acid amides  Secondary alcohols  Guanidines  Primary carboxylic acid amides  Propargyl-type 1,3-dipolar organic compounds  Carboximidamides  Hydrocarbon derivatives  Carbonyl compounds  Monoalkylamines  Organic oxides  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Alpha-oligopeptide - Phenylalanine or derivatives - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - N-acyl-amine - Fatty amide - Benzenoid - Monocyclic benzene moiety - Fatty acyl - Secondary alcohol - Secondary carboxylic acid amide - Carboxamide group - Guanidine - Amino acid or derivatives - Primary carboxylic acid amide - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Primary amine - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Alcohol - Hydrocarbon derivative - Amine - Organic oxide - Organooxygen compound - Primary aliphatic amine - Organonitrogen compound - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
External Descriptors Not available

Associated Targets(Human)

F2R Tclin Proteinase-activated receptor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Storage and Shipping

CAS rp175274

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names PEPTIDE1{T.F.L.L.R.[am]}$$$$;Thr-Phe-Leu-Leu-Arg-amide
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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