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Tenuifoliside A , CAS No.139726-35-5

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Item Number
T412630
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T412630-1mg
1mg
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$101.90

Basic Description

Synonyms NCGC00347659-02 | NCGC00347659-02_C31H38O17_3-O-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-beta-D-fructofuranosyl 6-O-(4-hydroxybenzoyl)-alpha-D-glucopyranoside | Tenuifoliside A | .ALPHA.-D-GLUCOPYRANOSIDE, 3-O-((2E)-1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2
Biochemical and Physiological Mechanisms Tenuifoliside A has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells. Tenuifoliside A is isolated from Polygala tenuifolia.
Storage Temp Store at -20°C
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Product Description

Information

Tenuifoliside A has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells. Tenuifoliside A is isolated from Polygala tenuifolia.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Cinnamic acids and derivatives
Subclass Hydroxycinnamic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent Coumaric acids and derivatives
Alternative Parents Cinnamic acid esters  p-Hydroxybenzoic acid alkyl esters  C-glycosyl compounds  Disaccharides  O-glycosyl compounds  Styrenes  Anisoles  Benzoyl derivatives  Phenoxy compounds  Methoxybenzenes  1-hydroxy-2-unsubstituted benzenoids  Alkyl aryl ethers  Fatty acid esters  Ketals  Oxanes  Dicarboxylic acids and derivatives  Enoate esters  Oxolanes  Secondary alcohols  Polyols  Oxacyclic compounds  Carbonyl compounds  Hydrocarbon derivatives  Primary alcohols  Organic oxides  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Coumaric acid or derivatives - Cinnamic acid ester - Disaccharide - P-hydroxybenzoic acid alkyl ester - P-hydroxybenzoic acid ester - Glycosyl compound - O-glycosyl compound - C-glycosyl compound - Benzoate ester - Benzoic acid or derivatives - Methoxybenzene - Phenoxy compound - Phenol ether - Anisole - Benzoyl - Styrene - 1-hydroxy-2-unsubstituted benzenoid - Fatty acid ester - Alkyl aryl ether - Ketal - Phenol - Benzenoid - Oxane - Dicarboxylic acid or derivatives - Fatty acyl - Monocyclic benzene moiety - Oxolane - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Carboxylic acid ester - Secondary alcohol - Acetal - Oxacycle - Organoheterocyclic compound - Polyol - Carboxylic acid derivative - Ether - Organic oxygen compound - Alcohol - Primary alcohol - Organic oxide - Carbonyl group - Organooxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as coumaric acids and derivatives. These are aromatic compounds containing Aromatic compounds containing a cinnamic acid moiety (or a derivative thereof) hydroxylated at the C2 (ortho-), C3 (meta-), or C4 (para-) carbon atom of the benzene ring.
External Descriptors Not available

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name [(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2S,3S,4R,5R)-4-hydroxy-2,5-bis(hydroxymethyl)-3-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyoxolan-2-yl]oxyoxan-2-yl]methyl 4-hydroxybenzoate
INCHI InChI=1S/C31H38O17/c1-41-18-10-15(11-19(42-2)27(18)43-3)4-9-22(35)46-28-24(37)20(12-32)47-31(28,14-33)48-30-26(39)25(38)23(36)21(45-30)13-44-29(40)16-5-7-17(34)8-6-16/h4-11,20-21,23-26,28,30,32-34,36-39H,12-14H2,1-3H3/b9-4+/t20-,21-,23-,24-,25+,26-,28+,30-,31+/m1/s1
InChIKey BBUQNXDJRVCZTI-FNUXIAMKSA-N
Smiles COC1=CC(=CC(=C1OC)OC)C=CC(=O)OC2C(C(OC2(CO)OC3C(C(C(C(O3)COC(=O)C4=CC=C(C=C4)O)O)O)O)CO)O
Isomeric SMILES COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)O[C@H]2[C@@H]([C@H](O[C@@]2(CO)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COC(=O)C4=CC=C(C=C4)O)O)O)O)CO)O
PubChem CID 46933844
Molecular Weight 682.6

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 682.600 g/mol
XLogP3 -0.500
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 17
Rotatable Bond Count 15
Exact Mass 682.211 Da
Monoisotopic Mass 682.211 Da
Topological Polar Surface Area 250.000 Ų
Heavy Atom Count 48
Formal Charge 0
Complexity 1050.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 9
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 1
Covalently-Bonded Unit Count 1

Solution Calculators

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