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Tea polyphenol - 10mM in DMSO, high purity , CAS No.84650-60-2

    Grade & Purity:
  • 10mM in DMSO
  • Cas Number:  84650-60-2
  • Molecular Weight:  458.4
  • PubChem CID: 1287
In stock
Item Number
T426207
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T426207-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$52.90
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Compound libraries (12325)

Basic Description

Synonyms DTXSID00859570 | FT-0686614 | 3,4,5-Trihydroxy-benzoic acid 5,7-dihydroxy-2-(3,4,5-trihydroxy-phenyl)-chroman-3-yl ester | CHEBI:182308 | E80553 | AKOS025248011 | FT-0604392 | HMS3651I16 | HMS3868K03 | B0005-465433 | [5,7-dihydroxy-2-(3,4,5-trihydroxyphen
Specifications & Purity 10mM in DMSO
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavans
Intermediate Tree Nodes Flavan-3-ols - Catechins
Direct Parent Catechin gallates
Alternative Parents Epigallocatechins  3'-hydroxyflavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  7-hydroxyflavonoids  Galloyl esters  p-Hydroxybenzoic acid alkyl esters  m-Hydroxybenzoic acid esters  1-benzopyrans  Pyrogallols and derivatives  Benzoyl derivatives  Alkyl aryl ethers  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Carboxylic acid esters  Monocarboxylic acids and derivatives  Oxacyclic compounds  Polyols  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Catechin gallate - Epigallocatechin - 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Hydroxyflavonoid - Galloyl ester - Gallic acid or derivatives - P-hydroxybenzoic acid alkyl ester - M-hydroxybenzoic acid ester - P-hydroxybenzoic acid ester - Benzoate ester - Chromane - Benzopyran - 1-benzopyran - Pyrogallol derivative - Benzenetriol - Benzoic acid or derivatives - Benzoyl - Alkyl aryl ether - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Monocyclic benzene moiety - Carboxylic acid ester - Carboxylic acid derivative - Polyol - Oxacycle - Ether - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as catechin gallates. These are organic compounds containing a gallate moiety glycosidically linked to a catechin.
External Descriptors Not available

Associated Targets(Human)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Names and Identifiers

IUPAC Name [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
INCHI InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2
InChIKey WMBWREPUVVBILR-UHFFFAOYSA-N
Smiles C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Molecular Weight 458.4
Reaxy-Rn 375093
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=375093&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 458.400 g/mol
XLogP3 1.200
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 4
Exact Mass 458.085 Da
Monoisotopic Mass 458.085 Da
Topological Polar Surface Area 197.000 Ų
Heavy Atom Count 33
Formal Charge 0
Complexity 667.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 2
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Chengguang Tian, Hong Xu, Jinxiang Dong.  (2024)  Development of environmentally friendly lubricant using natural resources: Layered double hydroxide gels.  INDUSTRIAL CROPS AND PRODUCTS,  208  (117879). 
2. Jiayin Liu, Jialing Tan, Hao Liu, Yunjie Yin, Chaoxia Wang.  (2023)  Multicolor-tunable biomass thermochromic dyes utilizing tea polyphenols color developer for temperature-controlled linen fabric.  INDUSTRIAL CROPS AND PRODUCTS,  204  (117254). 
3. Shibo Xu, Yiyi Lin, Xingjun Zhao, Zepeng Liang, Yanan Hu, Zhenhua Chen, Xiuli Ren, Xifan Mei.  (2023)  NIR triggered photocatalytic and photothermal bifunctional MOF nanozyme using for improving osteoarthritis microenvironment by repairing injured chondrocytes of mitochondria.  CHEMICAL ENGINEERING JOURNAL,  468  (143826). 
4. Xinlei Zhao, Xue Yang, Yihong Bao, Yang Guo, Jiayuan Luo, Shilong Jiang, Wei Zhang.  (2023)  Construction of vitamin D delivery system based on pine nut oil Pickering emulsion: effect of phenols.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (8): (4034-4046). 
5. Jian Xu, Jiuyun Cui, Haotian Sun, Yuting Wu, Changguo Xue, Atian Xie, Chengcai Li.  (2023)  Facile preparation of hydrophilic PVDF membrane via tea polyphenols modification for efficient oil-water emulsion separation.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  657  (130639). 
6. Yingjie Luo, Yiwei Zhang, Cimin Tao, Hongfei Ni, Xuesong Liu, Yong Chen, Yongjiang Wu, Hang Song, Tengfei Xu.  (2022)  Exploring the Absorption Mechanisms of Imidazolium-Based Ionic Liquids to Epigallocatechin Gallate.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  23  (20): (12600). 
7. Henghui Zhang, Xiaoli Wang, Dongliang He, Dongliang Zou, Runzhu Zhao, Huifang Wang, Shuying Li, Yongping Xu, Buhailiqiemu Abudureheman.  (2022)  Optimization of Flavonoid Extraction from Xanthoceras sorbifolia Bunge Flowers, and the Antioxidant and Antibacterial Capacity of the Extract.  MOLECULES,  27  (1): (113). 
8. Xueming Bao, Biaobiao Yan, Yuanyuan Yu, Bo Xu, Li Cui, Man Zhou, Qiang Wang, Ping Wang.  (2024)  A facile cellulose finishing strategy through in-situ growth of sliver-doped manganese dioxide assisted by amine-quinone for improving indoor living quality.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  267  (131448). 
9. Jialuo Chen, Zhipeng Li, Xinpeng Chen, Yurong Sun, Jin Cheng, Aijing Li, Shenzhou Lu, Tieling Xing.  (2024)  Bioinspired Design of an Underwater Adhesive Based on Tea Polyphenol-Modified Silk Fibroin.  ACS Biomaterials Science & Engineering,  11  (1): (343-353). 
10. Wei Li, Shengxian Chen, Yongqi Lu, Jiangjie Yu, Shiguang Zhao.  (2024)  Co-immobilization of laccase-mediator system to catalyze the synthesis of theaflavins from tea polyphenols.  Results in Engineering,  22  (102062). 
11. Nan Chen, Zi-Jian Feng, Hao-Xiang Gao, Qiang He, Wei-Cai Zeng.  (2024)  Core-shell structured alginate-based hydrogel beads modified by starch and protocatechuic acid: Preparation, characterization, phenolic slow release and stable antioxidant potential.  FOOD CHEMISTRY,  459  (140389). 
12. Yile Zhao, Zheng Wu, Chen Chen, Olaniyi Amos Fawole, Aili Jiang, Xiangzheng Yang, Da Wang, Xian Li, Di Wu, Kunsong Chen.  (2024)  Deacetylated konjac glucomannan films functionalised with carboxylated cellulose nanofiber and anti-browning components for fresh-cut apple preservation.  Food Packaging and Shelf Life,  46  (101389). 
13. Ge Song, Honglian Tan, Chuhan Cheng, Peng Li, Xinyang Sun, Yuling Zhou, Yong Fang.  (2024)  Development of a Fast Method Using Inductively Coupled Plasma Mass Spectrometry Coupled with High-Performance Liquid Chromatography and Exploration of the Reduction Mechanism of Cr(VI) in Foods.  Toxics,  12  (5): (325). 
14. Jing Chen, Jin Zhang, Rundong Liang, Mingyue Ma, Yan Cui.  (2024)  Development of magnetic ionic liquid-based ultrasound-assisted method for green walnut husk naphthoquinone pigments extraction and application of the pigment to black hair dye.  Sustainable Chemistry and Pharmacy,  42  (101840). 
15. Yuxin Li, Ziqi Hua, Yangjing Li, Tao Chen, Abdulhakeem S. Alamri, Yu Xu, Wei Gong, Yiyang Hou, Majid Alhomrani, Jiangning Hu.  (2024)  Development of multifunctional chitosan-based composite film loaded with tea polyphenol nanoparticles for strawberry preservation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,    (133648). 
16. Haijun Chang, Yu Hu, Yuanwei Shi, Jie Xiong, Zhaoying Bo.  (2024)  Effects of Gnaphalium affine Extract on the Gel Properties of •OH-Induced Oxidation of Myofibrillar Proteins.  Foods,  13  (10): (1447). 
17. Jianfeng Zhou, Weiqiang Wang, Xingjian Yang, Deng-Guang Yu, Ping Liu.  (2024)  Electrospun gelatin/tea polyphenol@pullulan nanofibers for fast-dissolving antibacterial and antioxidant applications.  JOURNAL OF FOOD SCIENCE,  89  (11): (7803-7818). 
18. Yaoqi Chen, Xu Cao, Jie Yao, Zeming Hu, Yang Luo, Gonghui Li, Hua Zhang, Kerong Wu.  (2024)  Enhancing under-urine adhesion and bladder adaptation of silk fibroin hydrogels with tea polyphenols for hemorrhagic cystitis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  283  (137487). 
19. Siqun Liu, Meirong Xu, Yuxin Guo, Yexia Xiao, Huifang Wang, Xianghua Gao, Xiaojie Lian, Baolong Niu, Wenfeng Li.  (2024)  Fabrication of an antibacterial system of arginine-modified chitosan with AgNPs-loaded montmorillonite for food preservation.  FOOD HYDROCOLLOIDS,  156  (110258). 
20. Yiming Chen, Huiying Li, Renfeng Xu, Yan Fang, Qinhui Chen, Zhengchao Wang, Haiqing Liu, Yunxiang Weng.  (2024)  Ferried Albumin-Inspired Bioadhesive with Dynamic Interfacial Bonds for Emergency Rescue.  Advanced Healthcare Materials,    (2400033). 
21. Danya Zhan, Qiongfen Yu, Ming Li, Ying Liu, Shengnan Sun, Rong Zhu, Run Zhang, Zhongfan Mo, Runfang Ma.  (2024)  Green Synthesis of Antioxidant and Degradable Biomass-Based Preservative Films for Efficient Strawberry Preservation.  ACS Food Science & Technology,  (12): (3135-3148). 
22. Yuci Xin, Yong Wu, Xingan Dong, Yuhan Li, Zhenxiang Cheng, Jianli Wang, Xiaolong Guo, Peng Yu.  (2025)  Manipulating the d- and p-Band centers of amorphous alloys by variable composition for robust oxygen evolution reaction.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  680  (417). 
23. Yongxuan Xiang, Wang Jiapeng, Yifeng Wang, Yurong Sun, Guoqiang Chen, Xueni Hou, Tieling Xing.  (2025)  Preparation and Properties of Colored Silk fibers for Wigs Based on Biomass Polyphenols.  DYES AND PIGMENTS,    (112788). 
24. Liya Fan, Xiaoxuan Xi, Xiaoyan Zhao, Xiao Zhu.  (2025)  Preparation of composite hydrogel with mechanical stability and temperature response for tea polyphenol release.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  707  (135831). 
25. Chunmeng Ding, Yuexing Zhu, Zhiyuan Huo, Shouzhi Yang, Yan Zhou, Ayizekeranmu Yiming, Wei Chen, Shanrong Liu, Kun Qian, Lin Huang.  (2024)  Pt/NiFe-LDH hybrids for quantification and qualification of polyphenols.  Materials Today Bio,  26  (101047). 
26. Jiayin Liu, Jialing Tan, Hao Liu, Chaoxia Wang.  (2025)  Shape-stabilized flexible thermochromic films with one-sided adhesion via gradient crosslinking strategy for temperature indicating.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  677  (120). 
27. Niu Jichao, You Tingting, Wang Xin, Ya Hanqin, Liang Shanshan, Zhao Ruobing, Ma Yongqiang.  (2024)  Study on stability and in vitro digestion property of Lutein Pickering emulsions encapsulated with whey protein isolate /sodium alginate/tea polyphenols.  Journal of Food Measurement and Characterization,    (1-16). 
28. Huan Liu, Ronger Ai, Bi-zhi Liu, Li He.  (2024)  Tea polyphenol nano-crosslinked dynamical hyaluronic acid-based hydrogel for diabetic wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  282  (136856). 
29. Weimian Zhou, Qun Yang, Sixuan Tao, Jin Cui, Jie Zhu, Siyu Zhou, Ruimiao Li, Juan Su, Ning Zhang, Lihui Xu, Hong Pan, Jiping Wang.  (2024)  Utilization of Tea Polyphenols as Color Developers in Reversible Thermochromic Dyes for Thermosensitive Color Change and Enhanced Functionality of Polyester Fabrics.  MOLECULES,  29  (20): (4944). 

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