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tCFA15 - 99%, high purity , CAS No.220757-88-0

COA

Grade & Purity:

≥99%

Cas Number: 220757-88-0
Molecular Weight: 364.6
PubChem CID: 9799188

In stock

Item Number

T649810

Grouped product items
SKU	Size	Availability	Price
T649810-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
T649810-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$580.90
T649810-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90
T649810-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,450.90

View related series

Neuronal Signaling (3320) Notch (41) Stem Cell/Wnt (1019)

Basic Description

Synonyms	tCFA15 \| 2-Cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- \| SCHEMBL580196 \| 3-(15-HYDROXYPENTADECYL)-2,4,4-TRIMETHYLCYCLOHEX-2-EN-1-ONE \| DTXSID30430917 \| HY-104031 \| VIA75788 \| 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one \| 2,
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling. In Vitro tCFA15 (10 nM-1 μM) dose-dependently affects the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and such effect is via Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures. tCFA15 stimulates arginine Vasotocin secretion in nerve terminals of the neurohypophysis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Oil IC50& Target:Notch1

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Fatty Acyls
    - Subclass Fatty alcohols

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Fatty Acyls
Subclass	Fatty alcohols
Intermediate Tree Nodes	Not available
Direct Parent	Long-chain fatty alcohols
Alternative Parents	Cyclohexenones Primary alcohols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homomonocyclic compounds
Substituents	Long chain fatty alcohol - Cyclohexenone - Cyclic ketone - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as long-chain fatty alcohols. These are fatty alcohols that have an aliphatic tail of 13 to 21 carbon atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(15-hydroxypentadecyl)-2,4,4-trimethylcyclohex-2-en-1-one
INCHI	InChI=1S/C24H44O2/c1-21-22(24(2,3)19-18-23(21)26)17-15-13-11-9-7-5-4-6-8-10-12-14-16-20-25/h25H,4-20H2,1-3H3
InChIKey	FGMAOXGOTRUOKJ-UHFFFAOYSA-N
Smiles	CC1=C(C(CCC1=O)(C)C)CCCCCCCCCCCCCCCO
Isomeric SMILES	CC1=C(C(CCC1=O)(C)C)CCCCCCCCCCCCCCCO
PubChem CID	9799188
Molecular Weight	364.6

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 130 mg/mL (356.56 mM; Need ultrasonic)
Molecular Weight	364.600 g/mol
XLogP3	7.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	15
Exact Mass	364.334 Da
Monoisotopic Mass	364.334 Da
Topological Polar Surface Area	37.300 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	420.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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