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TC NTR1 17 - 98%, high purity , CAS No.1146757-96-1

COA

Grade & Purity:

≥98%

Cas Number: 1146757-96-1
Molecular Weight: 522.98
PubChem CID: 56660273

In stock

Item Number

T286902

Grouped product items
SKU	Size	Availability	Price
T286902-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
T286902-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$229.90
T286902-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$333.90

Selective NTS1partial agonist

Basic Description

Synonyms	ML 301 analog \| N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50<15.6 nM and Emax= 63% of neurotensin response in Ca2+mobilization assay). Exhibits over 50-fold selectivity for NTS1over NTS2and GPR35.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Non-peptide Neurotensin Receptor 1 (NTS1) partial agonist (EC50 <15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). Exhibits over 50-fold selectivity for NTS1 over NTS2 and GPR35.

Names and Identifiers

IUPAC Name	2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-4-methylpentanoic acid
INCHI	InChI=1S/C27H27ClN4O5/c1-15(2)12-20(27(34)35)30-26(33)19-14-22(25-23(36-3)6-5-7-24(25)37-4)32(31-19)21-10-11-29-18-13-16(28)8-9-17(18)21/h5-11,13-15,20H,12H2,1-4H3,(H,30,33)(H,34,35)
InChIKey	ZQUSYVORYNBGLG-UHFFFAOYSA-N
Smiles	CC(C)CC(C(=O)O)NC(=O)C1=NN(C(=C1)C2=C(C=CC=C2OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl
Isomeric SMILES	CC(C)CC(C(=O)O)NC(=O)C1=NN(C(=C1)C2=C(C=CC=C2OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl
PubChem CID	56660273
Molecular Weight	522.98

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 52.3, Max Conc. mM: 100; Solvent:1eq. NaOH, Max Conc. mg/mL: 26.15, Max Conc. mM: 50
Sensitivity	Moisture sensitive; Light sensitive; Heat sensitive

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