Pteridines and derivatives

2-chloro-8-methyl-5,7-dihydropteridin-6-one

Grade & Purity:

≥97%

Cas Number: 944580-73-8 Compound CID: 29919671

Formula: C₇H₇ClN₄O Molecular Weight: 198.61

IUPAC Name: 2-chloro-8-methyl-5,7-dihydropteridin-6-one

SMILES: CN1CC(=O)NC2=CN=C(N=C21)Cl

InChIKey: CVRWNGLANPUNMW-UHFFFAOYSA-N

InChI: InChI=1S/C7H7ClN4O/c1-12-3-5(13)10-4-2-9-7(8)11-6(4)12/h2H,3H2,1H3,(H,10,13)

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2-chloro-8-methyl-6,7-dihydro-5H-pteridine

Grade & Purity:

≥97%

Cas Number: 1314916-25-0 Compound CID: 55252657

Formula: C₇H₉ClN₄ Molecular Weight: 184.62

SMILES: CN1CCNC2=CN=C(N=C21)Cl

InChIKey: JAOCALWYCRAAPN-UHFFFAOYSA-N

InChI: InChI=1S/C7H9ClN4/c1-12-3-2-9-5-4-10-7(8)11-6(5)12/h4,9H,2-3H2,1H3

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2-chloro-4,8-dimethyl-5,7-dihydropteridin-6-one

Grade & Purity:

≥97%

Cas Number: 1703018-82-9 Compound CID: 108142013

Formula: C₈H₉ClN₄O Molecular Weight: 212.63

SMILES: CC1=C2C(=NC(=N1)Cl)N(CC(=O)N2)C

InChIKey: CUKKVAARZBITCQ-UHFFFAOYSA-N

InChI: InChI=1S/C8H9ClN4O/c1-4-6-7(12-8(9)10-4)13(2)3-5(14)11-6/h3H2,1-2H3,(H,11,14)

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LY 345899

Grade & Purity:

≥98%

Cas Number: 10538-99-5 Compound CID: 135484014

Formula: C₂₀H₂₁N₇O₇ Molecular Weight: 471.4

IUPAC Name: (2S)-2-[[4-(3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid

SMILES: C1C2CN(C(=O)N2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O

InChIKey: JSNFRYBHBVDHSG-KIYNQFGBSA-N

InChI: InChI=1S/C20H21N7O7/c21-19-24-15-14(17(31)25-19)27-11(7-22-15)8-26(20(27)34)10-3-1-9(2-4-10)16(30)23-12(18(32)33)5-6-13(28)29/h1-4,11-12H,5-8H2,(H,23,show more

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5-Methyltetrahydrofolic acid

Grade & Purity:

≥95%

Cas Number: 134-35-0

Formula: C₂₀H₂₅N₇O₆ Molecular Weight: 459.46

IUPAC Name: (2S)-2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

SMILES: CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O

InChIKey: ZNOVTXRBGFNYRX-ABLWVSNPSA-N

InChI: InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24show more

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(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-5,6,7,8-tetrahydropteridin-6-one

Grade & Purity:

≥97%

Cas Number: 755039-55-5 EC Number: 875-055-4 Compound CID: 24820413

Formula: C₁₄H₁₉ClN₄O Molecular Weight: 294.78

IUPAC Name: (7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one

SMILES: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)Cl)C

InChIKey: RDOMCFLYXZACAX-SNVBAGLBSA-N

InChI: InChI=1S/C14H19ClN4O/c1-3-10-13(20)18(2)11-8-16-14(15)17-12(11)19(10)9-6-4-5-7-9/h8-10H,3-7H2,1-2H3/t10-/m1/s1

Synonyms: (7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-5,6,7,8-tetrahydropteridin-6-one | (7R)-2-chloro-8-cyclopentyl-7-ethyl-5...

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dual BRD4/PLK1 inhibitor 23

Grade & Purity:

Moligand™

IUPAC Name: (R)-4-((8-Cyclopentyl-5,7-dimethyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-(cyclopentyloxy)-N-(1-methylpiperidin-4-yl)benzamide

SMILES: CN1CCC(CC1)NC(=O)c1ccc(c(c1)OC1CCCC1)Nc1ncc2c(n1)N(C1CCCC1)C(C(=O)N2C)C

InChIKey: HTPNGOWITIWAHM-UHFFFAOYSA-N

InChI: InChI=1S/C31H43N7O3/c1-20-30(40)37(3)26-19-32-31(35-28(26)38(20)23-8-4-5-9-23)34-25-13-12-21(18-27(25)41-24-10-6-7-11-24)29(39)33-22-14-16-36(2)17-15-show more

Synonyms: compound 23

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[³H]N⁵-methylfolate

Grade & Purity:

Moligand™

IUPAC Name: 2-[[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

SMILES: OC(=O)CCC(C(=O)O)NC(=O)c1ccc(cc1)NCC1CNc2c(N1C)c(=O)nc([nH]2)N

InChIKey: ZNOVTXRBGFNYRX-UHFFFAOYSA-N

InChI: InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24show more

Synonyms: 5-Methyl THF | SCHEMBL79039 | BCP20912 | methyl THF | (S)-2-(4-(((S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropter...

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(R)-4-((8-Cyclopentyl-5-methyl-6-oxo-7-propyl-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide

Grade & Purity:

Moligand™

IUPAC Name: (R)-4-((8-Cyclopentyl-5-methyl-6-oxo-7-propyl-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide

SMILES: CCCC1N(C2CCCC2)c2nc(ncc2N(C1=O)C)Nc1ccc(cc1OC)C(=O)NC1CCN(CC1)C

InChIKey: ZUJOXCIHOKDDRE-UHFFFAOYSA-N

InChI: InChI=1S/C29H41N7O3/c1-5-8-23-28(38)35(3)24-18-30-29(33-26(24)36(23)21-9-6-7-10-21)32-22-12-11-19(17-25(22)39-4)27(37)31-20-13-15-34(2)16-14-20/h11-12show more

Synonyms: compound 6

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(R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one

Grade & Purity:

≥95%

Cas Number: 877676-50-1 EC Number: ‘807-904-1 Compound CID: 58405561

Formula: C₁₂H₁₇ClN₄O Molecular Weight: 268.74

IUPAC Name: (7R)-2-chloro-7-ethyl-5-methyl-8-propan-2-yl-7H-pteridin-6-one

SMILES: CCC1C(=O)N(C2=CN=C(N=C2N1C(C)C)Cl)C

InChIKey: RKXHCGYXHHPYHQ-MRVPVSSYSA-N

InChI: InChI=1S/C12H17ClN4O/c1-5-8-11(18)16(4)9-6-14-12(13)15-10(9)17(8)7(2)3/h6-8H,5H2,1-4H3/t8-/m1/s1

Synonyms: (R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one | (7R)-2-chloro-7-ethyl-5-methyl-8-propan-2-y...

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Methotrexate hydrate

Grade & Purity:

PharmPure™

USP

Cas Number: 133073-73-1 Compound CID: 165528

Formula: C₂₀H₂₂N₈O₅·xH₂O Molecular Weight: 454.44 (anhydrous basis)

IUPAC Name: (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;hydrate

SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O.O

InChIKey: FPJYMUQSRFJSEW-ZOWNYOTGSA-N

InChI: InChI=1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(Hshow more

Synonyms: Methylaminopterin hydrate | Antifolan hydrate | L-Amethopterin hydrate | L-4-Amino-N10-methylpteroylglutamic acid hyd...

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(±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride

Grade & Purity:

≥95%

Cas Number: 69113-63-9 Compound CID: 135445757

Formula: C₇H₁₁N₅O・2HCl Molecular Weight: 254.12

IUPAC Name: 2-amino-6-methyl-5,6,7,8-tetrahydro-3H-pteridin-4-one;dihydrochloride

SMILES: CC1CNC2=C(N1)C(=O)NC(=N2)N.Cl.Cl

InChIKey: MKQLORLCFAZASZ-UHFFFAOYSA-N

InChI: InChI=1S/C7H11N5O.2ClH/c1-3-2-9-5-4(10-3)6(13)12-7(8)11-5;;/h3,10H,2H2,1H3,(H4,8,9,11,12,13);2*1H

Synonyms: 2-amino-6-methyl-5,6,7,8-tetrahydro-3H-pteridin-4-one;dihydrochloride | 2-Amino-6-methyl-5,6,7,8-tetrahydropteridin-4...

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Pteridines and derivatives

Description:

Ancestors: