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Taxifolin - analytical standard,≥98%, high purity , CAS No.480-18-2

In stock
Item Number
T117991
Grouped product items
SKU Size
Availability
Price Qty
T117991-25mg
25mg
4
$39.90
T117991-100mg
100mg
1
$89.90
T117991-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$159.90
T117991-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$399.90

Basic Description

Synonyms 2,3-Dihydroquercetin | Lariksin | (+)-Dihydroquercetin | Distylin | Lavitol | (+)-(2R,3R)-dihydroquercetin | (+/-)-Taxifolin | Diquertin | Taxifoliol | (+)-Taxifolin | Flamena D | TAXIFOLIN | dihydroquercetin | (2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone
Specifications & Purity analytical standard, ≥98%
Storage Temp Store at 2-8°C,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade analytical standard
Product Description

Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.

Application:
Taxifolin can be used as a reference standard for the determination of taxifolin in plasma of rabbit using high performance liquid chromatography technique(HPLC).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavans
Intermediate Tree Nodes Flavanones
Direct Parent Flavanonols
Alternative Parents 3'-hydroxyflavonoids  3-hydroxyflavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  7-hydroxyflavonoids  Chromones  Catechols  Aryl alkyl ketones  1-hydroxy-2-unsubstituted benzenoids  1-hydroxy-4-unsubstituted benzenoids  Alkyl aryl ethers  Benzene and substituted derivatives  Vinylogous acids  Secondary alcohols  Oxacyclic compounds  Polyols  Hydrocarbon derivatives  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Hydroxyflavonoid - Flavanonol - 3'-hydroxyflavonoid - 3-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Chromone - Benzopyran - 1-benzopyran - Chromane - Catechol - Aryl alkyl ketone - Aryl ketone - Phenol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Secondary alcohol - Ketone - Polyol - Organoheterocyclic compound - Oxacycle - Ether - Organooxygen compound - Organic oxide - Organic oxygen compound - Alcohol - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as flavanonols. These are compounds containing a flavan-3-one moiety, with a structure characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a hydroxyl group and a ketone at the carbon C2 and C3, respectively.
External Descriptors Dihyroflavonols

Associated Targets(Human)

CA12 Tclin Carbonic anhydrase 12 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one
INCHI InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
InChIKey CXQWRCVTCMQVQX-LSDHHAIUSA-N
Smiles C1=CC(=C(C=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
Isomeric SMILES C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
Alternate CAS 17654-26-1
PubChem CID 439533
Molecular Weight 304.25
Beilstein 5299277

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number Certificate Type Date Item
H2310056 Certificate of Analysis May 12, 2025 T117991
H2422514 Certificate of Analysis Aug 09, 2024 T117991
H2422515 Certificate of Analysis Aug 09, 2024 T117991
H2422525 Certificate of Analysis Aug 09, 2024 T117991
I2214741 Certificate of Analysis Jun 20, 2024 T117991
I2103432 Certificate of Analysis Jun 07, 2023 T117991
D2014038 Certificate of Analysis Feb 18, 2022 T117991
C1412096 Certificate of Analysis Jan 27, 2022 T117991

Chemical and Physical Properties

Sensitivity Heat sensitive; Air sensitive
Melt Point(°C) 242 °C
Molecular Weight 304.250 g/mol
XLogP3 1.500
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 1
Exact Mass 304.058 Da
Monoisotopic Mass 304.058 Da
Topological Polar Surface Area 127.000 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 428.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Chengyun He, Lu Bai, Daqun Liu, Benguo Liu.  (2023)  Interaction mechanism of okra (Abelmoschus esculentus L.) seed protein and flavonoids: Fluorescent and 3D-QSAR studies.  Food Chemistry-X,  20  (101023). 
2. Xia Chenjie, Zhu Hongliu, Hu Changhui, Liu Jie, Hua Haibing, Yang Jianqiu, Chen Zhipeng, Gao Yihong.  (2023)  Simultaneous Determination of Three Flavonoids in Rat Plasma of Masson Pinus Needles (Pinus massoniana L.) Extracts by UHPLC-MS/MS and Application to Pharmacokinetics Studies after Oral and Transdermal Administration.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,     
3. Yuan Meng, Zihao Wei, Changhu Xue.  (2023)  Deciphering the interaction mechanism and binding mode between chickpea protein isolate and flavonoids based on experimental studies and molecular simulation.  FOOD CHEMISTRY,  429  (136848). 
4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen.  (2023)  Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential.  Food Bioscience,  52  (102508). 
5. Leyong Yuan, Yan Sun, Ning Zhou, Weipeng Wu, Weidong Zheng, Yukun Wang.  (2022)  Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway.  Frontiers in Pharmacology,  13  (845600). 
6. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074). 
7. Chengshuai Li, Lijing Zhang, Decao Niu, Shuzhen Nan, Xiumei Miao, Xiaowei Hu, Hua Fu.  (2021)  Investigation of flavonoid expression and metabolite content patterns during seed formation of Artemisia sphaerocephala Krasch..  SEED SCIENCE RESEARCH,  31  (2): (136-148). 
8. Hao Liu, Chenyun Gan, Houyin Shi, Kunyan Qu, Liuyang Jing, Muhe Lu, Benyu Su, Huayang Yu, Hang Yuan, Jingjing Chen, Ruirui Zhang, Weiling Zeng.  (2021)  Gastric floating pill enhances the bioavailability and drug efficacy of dihydromyricetin in vivo.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,  61  (102279). 
9. Chaonan Su, Caihong Li, Kang Sun, Wenjing Li, Rongxia Liu.  (2020)  Quantitative analysis of bioactive components in walnut leaves by UHPLC-Q-Orbitrap HRMS combined with QAMS.  FOOD CHEMISTRY,  331  (127180). 
10. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song.  (2020)  Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  239  (118519). 
11. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang.  (2020)  Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations.  FOOD CHEMISTRY,  323  (126807). 
12. Xiaoqin Wang, Wencong Jia, Guoyin Lai, Lijuan Wang, María del Mar Contreras, Daomao Yang.  (2020)  Extraction for profiling free and bound phenolic compounds in tea seed oil by deep eutectic solvents.  JOURNAL OF FOOD SCIENCE,  85  (5): (1450-1461). 
13. Rongxia Liu, Chaonan Su, Yumeng Xu, Kangle Shang, Kang Sun, Caihong Li, Jing Lu.  (2020)  Identifying potential active components of walnut leaf that action diabetes mellitus through integration of UHPLC-Q-Orbitrap HRMS and network pharmacology analysis.  JOURNAL OF ETHNOPHARMACOLOGY,  253  (112659). 
14. Long Ma, Xiuqi Cao, Haiyue Wang, Kui Lu, Ying Wang, Chunhao Tu, Yujie Dai, Yuanyuan Meng, Yuyin Li, Peng Yu, Shuli Man, Aipo Diao.  (2019)  Discovery of Myricetin as a Potent Inhibitor of Human Flap Endonuclease 1, Which Potentially Can Be Used as Sensitizing Agent against HT-29 Human Colon Cancer Cells.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  67  (6): (1656–1665). 
15. Qian Liu, Hai-Long Wu, Zhi Liu, Rong Xiao, Tong Wang, Yong Hu, Yu-Jie Ding, Ru-Qin Yu.  (2018)  Chemometrics-assisted HPLC-DAD as a rapid and interference-free strategy for simultaneous determination of 17 polyphenols in raw propolis.  Analytical Methods,  10  (46): (5577-5588). 
16. Shuyu Shen, Rui Huang, Charlie Li, Wenyan Wu, Honglin Chen, John Shi, Shiguo Chen, Xingqian Ye.  (2018)  Phenolic Compositions and Antioxidant Activities Differ Significantly among Sorghum Grains with Different Applications.  MOLECULES,  23  (5): (1203). 
17. Han Peng, Zeyuan Deng, Xuan Chen, Yong Sun, Bing Zhang, Hongyan Li.  (2018)  Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,     
18. Jiang Liu, Xiansheng Wang, Sheng Geng, Benguo Liu, Guizhao Liang.  (2017)  Inhibitory Mechanism of Taxifolin against α-Glucosidase Based on Spectrofluorimetry and Molecular Docking.  Natural Product Communications,     
19. Wang Bohong, Qin Qian, Chang Mengmeng, Li Shuyan, Shi Xianzhe, Xu Guowang.  (2018)  Molecular interaction study of flavonoids with human serum albumin using native mass spectrometry and molecular modeling.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  410  (3): (827-837). 
20. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang.  (2017)  Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr).  Journal of Functional Foods,  32  (296). 
21. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan.  (2017)  The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.  FOOD CHEMISTRY,  224  (26). 
22. Qinqin Wang, Lu Wang, Gaiping Li, Baoxian Ye.  (2017)  A simple and sensitive method for determination of taxifolin on palladium nanoparticles supported poly (diallyldimethylammonium chloride) functionalized graphene modified electrode.  TALANTA,  164  (323). 
23. Jiazeng Yang,Jincai Liang,Lei Shao,Lihong Liu,Ke Gao,Jun-Liang Zhang,Zhenjiao Sun,Wendong Xu,Pengcheng Lin,Rongmin Yu,Jiachen Zi.  (2020-02-01)  Green production of silybin and isosilybin by merging metabolic engineering approaches and enzymatic catalysis..  Metabolic engineering,  59  (44-52). 
24. Wang Weiting, Fan Xuanxuan, Chen Naidong, Hao Jingwen, Zhang Manman, Xie Zhengjun.  (2025)  An Ultra-High Performance Liquid Chromatography-Mass Spectrometry Method Based on Solid Phase Extraction Was Developed for the Analysis of Polyphenols in Prunus Mume Sieb. et Zucc.  JOURNAL OF AOAC INTERNATIONAL,     
25. Xiaomeng Zhang, Xinquan Tian, Junyu Luo, Xiaoyang Wang, Shoupu He, Gaofei Sun, Ruidan Dong, Panhong Dai, Xiao Wang, Zhaoe Pan, Baojun Chen, Daowu Hu, Liru Wang, Baoyin Pang, Aishuang Xing, Guoyong Fu, Baoquan Wang, Jinjie Cui, Lei Ma, Xiongming Du.  (2025)  Identification of UDP-glucosyltransferase involved in the biosynthesis of phloridzin in Gossypium hirsutum.  PLANT JOURNAL,  121  (3): (e17248). 
26. Ye Wang, Shao-jie Chen, Ting Ma, Qiu Long, Lan Chen, Ke-xin Xu, Yu Cao.  (2024)  Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.  INTERNATIONAL IMMUNOPHARMACOLOGY,  138  (112517). 
27. Xiaomei Wen, Shanjie Han, Jiahui Wang, Yanxia Zhang, Lining Tan, Chen Chen, Baoyu Han, Mengxin Wang.  (2024)  The Flavor Characteristics, Antioxidant Capability, and Storage Year Discrimination Based on Backpropagation Neural Network of Organic Green Tea (Camellia sinensis) during Long-Term Storage.  Foods,  13  (5): (753). 

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