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TAS4464 hydrochloride - 98%, high purity , CAS No.1848959-11-4

COA

Grade & Purity:

≥98%

Cas Number: 1848959-11-4
Poids moléculaire: 542.97
PubChem CID: 124121823

En stock

Item Number

T649656

Articles du produit groupé
SKU	Taille	Disponibilité	Prix
T649656-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	152,90$US
T649656-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	320,90$US
T649656-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	520,90$US
T649656-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	1 040,90$US

View related series

Amino Acid/Protein Metabolism (1836) Metabolic Enzyme/Protease (4860) NEDD8-activating Enzyme (9)

Description générale

Spécifications et pureté	≥98%
Mécanismes biochimiques et physiologiques	TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM.
Température de stockage	Store at 2-8°C,Desiccated
Expédié en	Wet ice Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Product Description	TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM Form:Solid IC50& Target:IC50：0.955 nM (NAE)

Noms et identifiants

IUPAC Name	4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamoylamino)methyl]oxolan-2-yl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]pyrrolo[2,3-d]pyrimidine;hydrochloride
INCHI	InChI=1S/C21H23FN6O6S.ClH/c1-2-33-14-5-3-4-13(22)12(14)7-6-11-9-28(20-16(11)19(23)25-10-26-20)21-18(30)17(29)15(34-21)8-27-35(24,31)32;/h3-5,9-10,15,17-18,21,27,29-30H,2,8H2,1H3,(H2,23,25,26)(H2,24,31,32);1H/t15-,17-,18-,21-;/m1./s1
InChIKey	CDCFJYCKNAWPTL-WVAMHNCPSA-N
Smiles	CCOC1=C(C(=CC=C1)F)C#CC2=CN(C3=NC=NC(=C23)N)C4C(C(C(O4)CNS(=O)(=O)N)O)O.Cl
PubChem CID	124121823
Poids moléculaire	542.97

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Propriétés chimiques et physiques

Solubilité	DMSO : 83.33 mg/mL (153.47 mM; Need ultrasonic) H2O : 5 mg/mL (9.21 mM; ultrasonic and warming and heat to 60°C)

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