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Targets(Human)
GPNMB

GPNMB

Description	Transmembrane glycoprotein NMB

Gene and Protein Information

Gene ID	10457
Uniprot Accession IDs	Q14956 A4D155 Q6UVX1 Q8N1A1
Ensembl ID	ENSG00000136235
Symbol	HGFIN NMB NMB HGFIN PLCA3
Chromosome	7
Family	Belongs to the PMEL/NMB family.
Sequence	MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNCRNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFVTMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTSTLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463289	GPNMB	glycoprotein nmb	9598	VGNC:7386	OMA, EggNOG
Macaque	704990	GPNMB	glycoprotein nmb	9544		Inparanoid, OMA, EggNOG
Mouse	93695	Gpnmb	glycoprotein (transmembrane) nmb	10090	MGI:1934765	Inparanoid, OMA, EggNOG
Rat	113955	Gpnmb	glycoprotein nmb	10116	RGD:71008	Inparanoid, OMA, EggNOG
Dog	482355	GPNMB	glycoprotein nmb	9615	VGNC:41389	Inparanoid, OMA, EggNOG
Horse	100067870	GPNMB	glycoprotein nmb	9796	VGNC:18503	Inparanoid, OMA, EggNOG
Cow	509600	GPNMB	glycoprotein nmb	9913	VGNC:29541	Inparanoid, OMA, EggNOG
Opossum	100015939	GPNMB	glycoprotein nmb	13616		Inparanoid, OMA, EggNOG
Platypus	100082972	GPNMB	glycoprotein nmb	9258		Inparanoid, OMA, EggNOG
Chicken	428431	GPNMB	glycoprotein nmb	9031	CGNC:8320	Inparanoid, OMA, EggNOG
Anole lizard	100559072	gpnmb	glycoprotein nmb	28377		Inparanoid, OMA, EggNOG
Xenopus	100124325	gpnmb	glycoprotein nmb	8364	XB-GENE-983263	Inparanoid, OMA, EggNOG
Zebrafish	563348	gpnmb	glycoprotein (transmembrane) nmb	7955	ZDB-GENE-060503-106	OMA, EggNOG

Protein Classes

PANTHER Classes
protein / signaling molecule / cell adhesion molecule / Transmembrane glycoprotein NMB
protein / signaling molecule / membrane-bound signaling molecule / Transmembrane glycoprotein NMB

DTO Classes
protein / Signaling / Membrane-bound signaling molecule / Transmembrane glycoprotein NMB

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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