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SIGLEC8

Description Sialic acid-binding Ig-like lectin 8

Gene and Protein Information

Gene ID 27181
Uniprot Accession IDs Q9NYZ4 Q7Z728 Siglec-8
Ensembl ID ENSG00000105366
Symbol SAF2 SAF2 SIGLEC-8 SIGLEC8L
Chromosome 19
Family Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Sequence
MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPSSGEEGELHYATLSFHKVKPQDPQGQEATDSEYSEIKIHKRETAETQACLRNHNPSSKEVRG
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 107966154 SIGLEC8 sialic acid binding Ig like lectin 8 9598 VGNC:13310 Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    immunoglobulin superfamily cell adhesion molecule    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    immunoglobulin receptor superfamily    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    cytokine receptor    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    defense/immunity protein    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    membrane-bound signaling molecule    /    Sialic acid-binding Ig-like lectin 8
protein    /    receptor    /    myelin protein    /    Sialic acid-binding Ig-like lectin 8
DTO Classes
protein    /    Receptor    /    Cytokine receptor    /    Immunoglobulin receptor superfamily    /    Sialic acid-binding Ig-like lectin 8

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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