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Targets(Human)
TGFBR2

TGFBR2

Description	TGF-beta receptor type-2

Gene and Protein Information

Gene ID	7048
Uniprot Accession IDs	P37173 B4DTV5 Q15580 Q6DKT6 Q99474 TGFR-2
Ensembl ID	ENSG00000163513
Symbol	AAT3 FAA3 LDS2 MFS2 RIIC LDS1B LDS2B TAAD2 TBRII TBR-ii TGFR-2 TGFbeta-RII
Chromosome	3
Family	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence	MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	460243	TGFBR2	transforming growth factor beta receptor 2	9598	VGNC:9701	OMA, EggNOG
Macaque	703088	TGFBR2	transforming growth factor beta receptor 2	9544		Inparanoid, OMA, EggNOG
Mouse	21813	Tgfbr2	transforming growth factor, beta receptor II	10090	MGI:98729	Inparanoid, OMA, EggNOG
Rat	81810	Tgfbr2	transforming growth factor, beta receptor 2	10116	RGD:69651	Inparanoid, OMA, EggNOG
Dog	477039	TGFBR2	transforming growth factor beta receptor 2	9615	VGNC:47312	Inparanoid, OMA, EggNOG
Horse	100033860	TGFBR2	transforming growth factor beta receptor 2	9796	VGNC:24056	Inparanoid, OMA, EggNOG
Cow	535376	TGFBR2	transforming growth factor beta receptor 2	9913	VGNC:35805	Inparanoid, OMA, EggNOG
Opossum	100031897	TGFBR2	transforming growth factor beta receptor 2	13616		Inparanoid, OMA, EggNOG
Platypus		TGFBR2	transforming growth factor beta receptor 2 [Source:HGNC Symbol;Acc:HGNC:11773]	9258		OMA, EggNOG
Chicken	396399	TGFBR2	transforming growth factor beta receptor 2	9031	CGNC:8694	Inparanoid, OMA, EggNOG
Anole lizard	100552899	tgfbr2	transforming growth factor beta receptor 2	28377		Inparanoid, OMA, EggNOG
Xenopus	100488582	tgfbr2	transforming growth factor beta receptor II	8364	XB-GENE-485606	Inparanoid, OMA, EggNOG
Zebrafish	30739	tgfbr2b	transforming growth factor beta receptor 2b	7955	ZDB-GENE-980526-375	OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    TGF-beta receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Tgf-beta receptor type-2
protein    /    receptor    /    protein kinase    /    Tgf-beta receptor type-2
protein    /    receptor    /    transferase    /    Tgf-beta receptor type-2
protein    /    receptor    /    kinase    /    Tgf-beta receptor type-2

DTO Classes
protein / Kinase / Protein kinase / TKL group / STKR family / STKR Type 2 subfamily / Tgf-beta receptor type-2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

🔙[Back to Target (Human)]

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