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SCN10A

Description Sodium channel protein type 10 subunit alpha

Gene and Protein Information

Gene ID 6336
Uniprot Accession IDs Q9Y5Y9 A6NDQ1
Ensembl ID ENSG00000185313
Symbol PN3 SNS hPN3 FEPS2 Nav1.8
Chromosome 3
Family Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.8/SCN10A subfamily.
Sequence
MEFPIGSLETNNFRRFTPESLVEIEKQIAAKQGTKKAREKHREQKDQEEKPRPQLDLKACNQLPKFYGELPAELIGEPLEDLDPFYSTHRTFMVLNKGRTISRFSATRALWLFSPFNLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRTDLPEKIEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLAYVGTAIDLRGISGLRTFRVLRALKTVSVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKGNLKNKCVKNDMAVNETTNYSSHRKPDIYINKRGTSDPLLCGNGSDSGHCPDGYICLKTSDNPDFNYTSFDSFAWAFLSLFRLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILAVVTMAYEEQNQATTDEIEAKEKKFQEALEMLRKEQEVLAALGIDTTSLHSHNGSPLTSKNASERRHRIKPRVSEGSTEDNKSPRSDPYNQRRMSFLGLASGKRRASHGSVFHFRSPGRDISLPEGVTDDGVFPGDHESHRGSLLLGGGAGQQGPLPRSPLPQPSNPDSRHGEDEHQPPPTSELAPGAVDVSAFDAGQKKTFLSAEYLDEPFRAQRAMSVVSIITSVLEELEESEQKCPPCLTSLSQKYLIWDCCPMWVKLKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFFTAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAKKGSLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQLLGENYRNNRKNISAPHEDWPRWHMHDFFHSFLIVFRILCGEWIENMWACMEVGQKSICLILFLTVMVLGNLVVLNLFIALLLNSFSADNLTAPEDDGEVNNLQVALARIQVFGHRTKQALCSFFSRSCPFPQPKAEPELVVKLPLSSSKAENHIAANTARGSSGGLQAPRGPRDEHSDFIANPTVWVSVPIAEGESDLDDLEDDGGEDAQSFQQEVIPKGQQEQLQQVERCGDHLTPRSPGTGTSSEDLAPSLGETWKDESVPQVPAEGVDDTSSSEGSTVDCLDPEEILRKIPELADDLEEPDDCFTEGCIRHCPCCKLDTTKSPWDVGWQVRKTCYRIVEHSWFESFIIFMILLSSGSLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFEMLLKWVAYGFKKYFTNAWCWLDFLIVNISLISLTAKILEYSEVAPIKALRTLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVKVNFDNVAMGYLALLQVATFKGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGFFTLNLFVGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKILGKINQFFVAVFTGECVMKMFALRQYYFTNGWNVFDFIVVVLSIASLIFSAILKSLQSYFSPTLFRVIRLARIGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRGDCGSPAVGIIFFTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEKFDPEATQFITFSALSDFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDSLKANMEEKFMATNLSKSSYEPIATTLRWKQEDISATVIQKAYRSYVLHRSMALSNTPCVPRAEEEAASLPDEGFVAFTANENCVLPDKSETASATSFPPSYESVTRGLSDRVNMRTSSSIQNEDEATSMELIAPGP
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 460274 SCN10A sodium voltage-gated channel alpha subunit 10 9598 VGNC:12180 OMA, EggNOG
Macaque 694962 SCN10A sodium voltage-gated channel alpha subunit 10 9544 Inparanoid, OMA, EggNOG
Mouse 20264 Scn10a sodium channel, voltage-gated, type X, alpha 10090 MGI:108029 Inparanoid, OMA, EggNOG
Rat 29571 Scn10a sodium voltage-gated channel alpha subunit 10 10116 RGD:3629 Inparanoid, OMA, EggNOG
Dog 477026 SCN10A sodium voltage-gated channel alpha subunit 10 9615 VGNC:45913 Inparanoid, OMA, EggNOG
Horse 100055493 SCN10A sodium voltage-gated channel alpha subunit 10 9796 VGNC:22730 Inparanoid, OMA, EggNOG
Cow 100299477 SCN10A sodium voltage-gated channel alpha subunit 10 9913 VGNC:34343 Inparanoid, OMA, EggNOG
Pig 100518274 SCN10A sodium voltage-gated channel alpha subunit 10 9823 OMA, EggNOG
Opossum 100020766 SCN10A sodium voltage-gated channel alpha subunit 10 13616 Inparanoid, OMA, EggNOG
Anole lizard 100560187 LOC100560187 sodium channel protein type 5 subunit alpha 28377 OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 10 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 10 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.8/SCN10A subfamily    /    Sodium channel protein type 10 subunit alpha

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

🔙[Back to Target (Human)]

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