SCN7A

Description	Sodium channel protein type 7 subunit alpha

Gene and Protein Information

Gene ID	6332
Uniprot Accession IDs	Q01118
Ensembl ID	ENSG00000136546
Symbol	SCN6A NaG SCN6A Nav2.1 Nav2.2
Chromosome	2
Family	Belongs to the sodium channel (TC 1.A.1.10) family. SCN7A subfamily.
Sequence	MLASPEPKGLVPFTKESFELIKQHIAKTHNEDHEEEDLKPTPDLEVGKKLPFIYGNLSQGMVSEPLEDVDPYYYKKKNTFIVLNKNRTIFRFNAASILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSLTNLPKWRPVLENTLLGIYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTVFEVIIRYSPLDFIPTLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNLKHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALLCGNRTDAGQCPEGYVCVKAGINPDQGFTNFDSFGWALFALFRLMAQDYPEVLYHQILYASGKVYMIFFVVVSFLFSFYMASLFLGILAMAYEEEKQRVGEISKKIEPKFQQTGKELQEGNETDEAKTIQIEMKKRSPISTDTSLDVLEDATLRHKEELEKSKKICPLYWYKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANVAGMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLFGKNYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGEWVETLWDCMEVAGQSWCIPFYLMVILIGNLLVLYLFLALVSSFSSCKDVTAEENNEAKNLQLAVARIKKGINYVLLKILCKTQNVPKDTMDHVNEVYVKEDISDHTLSELSNTQDFLKDKEKSSGTEKNATENESQSLIPSPSVSETVPIASGESDIENLDNKEIQSKSGDGGSKEKIKQSSSSECSTVDIAISEEEEMFYGGERSKHLKNGCRRGSSLGQISGASKKGKIWQNIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKTIKILLEYADMIFTYIFILEMLLKWMAYGFKAYFSNGWYRLDFVVVIVFCLSLIGKTREELKPLISMKFLRPLRVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPTSGERFPSSEVMNKSRCESLLFNESMLWENAKMNFDNVGNGFLSLLQVATFNGWITIMNSAIDSVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLGGSNIFITVKQRKQYRRLKKLMYEDSQRPVPRPLNKLQGFIFDVVTSQAFNVIVMVLICFQAIAMMIDTDVQSLQMSIALYWINSIFVMLYTMECILKLIAFRCFYFTIAWNIFDFMVVIFSITGLCLPMTVGSYLVPPSLVQLILLSRIIHMLRLGKGPKVFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNFAYVKKEAGINDVSNFETFGNSMLCLFQVAIFAGWDGMLDAIFNSKWSDCDPDKINPGTQVRGDCGNPSVGIFYFVSYILISWLIIVNMYIVVVMEFLNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYIDSSKLSDFAAALDPPLFMAKPNKGQLIALDLPMAVGDRIHCLDILLAFTKRVMGQDVRMEKVVSEIESGFLLANPFKITCEPITTTLKRKQEAVSATIIQRAYKNYRLRRNDKNTSDIHMIDGDRDVHATKEGAYFDKAKEKSPIQSQI Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Macaque	704414	SCN7A	sodium voltage-gated channel alpha subunit 7	9544		Inparanoid, OMA, EggNOG
Mouse	20272	Scn7a	sodium channel, voltage-gated, type VII, alpha	10090	MGI:102965	Inparanoid, OMA
Rat	64155	Scn7a	sodium voltage-gated channel alpha subunit 7	10116	RGD:61922	Inparanoid, OMA
Dog	488382	SCN7A	sodium voltage-gated channel alpha subunit 7	9615	VGNC:45922	Inparanoid, OMA, EggNOG
Horse	100062186	SCN7A	sodium voltage-gated channel alpha subunit 7	9796	VGNC:22741	Inparanoid, OMA, EggNOG
Cow	507516	SCN7A	sodium voltage-gated channel alpha subunit 7	9913	VGNC:34353	Inparanoid, OMA, EggNOG
Pig	100516881	SCN7A	sodium voltage-gated channel alpha subunit 7	9823		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 7 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 7 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 7 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 7 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 7 subunit alpha

DTO Classes
protein / Ion channel / Sodium channel family / SCN7A subfamily / Sodium channel protein type 7 subunit alpha

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography