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ITK

Description	Tyrosine-protein kinase ITK/TSK

Gene and Protein Information

Gene ID	3702
Uniprot Accession IDs	Q08881 B2R752 Q32ML7
Ensembl ID	ENSG00000113263
Symbol	EMT LYK EMT LYK LPFS1 PSCTK2
Chromosome	5
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
Sequence	MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	735556	ITK	IL2 inducible T cell kinase	9598	VGNC:6939	OMA, EggNOG
Macaque	715471	ITK	IL2 inducible T-cell kinase	9544		Inparanoid, OMA, EggNOG
Mouse	16428	Itk	IL2 inducible T cell kinase	10090	MGI:96621	Inparanoid, OMA, EggNOG
Rat	363577	Itk	IL2-inducible T-cell kinase	10116	RGD:1311618	Inparanoid, OMA, EggNOG
Dog	489159	ITK	IL2 inducible T cell kinase	9615	VGNC:42149	Inparanoid, OMA, EggNOG
Horse	100071232	ITK	IL2 inducible T cell kinase	9796	VGNC:19189	Inparanoid, OMA, EggNOG
Cow	522311	ITK	IL2 inducible T cell kinase	9913	VGNC:30338	Inparanoid, OMA, EggNOG
Opossum	100030005	ITK	IL2 inducible T-cell kinase	13616		Inparanoid, EggNOG
Platypus		ITK	IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171]	9258		OMA, EggNOG
Chicken	416247	ITK	IL2 inducible T-cell kinase	9031	CGNC:2826	Inparanoid, OMA
Anole lizard	100554114	itk	IL2 inducible T-cell kinase	28377		Inparanoid, OMA
Zebrafish	798906	itk	IL2 inducible T cell kinase	7955	ZDB-GENE-990415-261	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TK group / TEC family / Tyrosine-protein kinase itk/tsk

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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