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HMGCS1

Description	Hydroxymethylglutaryl-CoA synthase, cytoplasmic

Gene and Protein Information

Gene ID	3157
Uniprot Accession IDs	Q01581 B2RDL8 HMG-CoA synthase
Ensembl ID	ENSG00000112972
Symbol	HMGCS HMGCS
Chromosome	5
Family	Belongs to the HMG-CoA synthase family.
Sequence	MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	461892	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9598	VGNC:4035	OMA, EggNOG
Macaque	702553	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9544		Inparanoid, OMA
Mouse	208715	Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	10090	MGI:107592	Inparanoid, OMA, EggNOG
Rat	29637	Hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1	10116	RGD:70970	Inparanoid, OMA, EggNOG
Dog	479344	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9615		Inparanoid, OMA, EggNOG
Horse	100065037	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9796	VGNC:18808	Inparanoid, OMA, EggNOG
Cow	407767	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9913	VGNC:29880	Inparanoid, OMA, EggNOG
Pig	100524223	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9823		Inparanoid, OMA, EggNOG
Opossum	100012956	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	13616		Inparanoid, OMA, EggNOG
Platypus	100075498	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	9258		Inparanoid, OMA, EggNOG
Anole lizard	100559772	hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1	28377		Inparanoid, OMA, EggNOG
Xenopus	100145212	hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1	8364	XB-GENE-942074	Inparanoid, OMA, EggNOG
Zebrafish	394060	hmgcs1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	7955	ZDB-GENE-040426-1042	Inparanoid, OMA
C. elegans	178956	hmgs-1	Hydroxymethylglutaryl-CoA synthase	6239		Inparanoid, OMA

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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