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| Description | Mismatch repair endonuclease PMS2 |
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Gene and Protein Information
| Gene ID | 5395 |
|---|---|
| Uniprot Accession IDs | P54278 B2R610 Q52LH6 Q5FBW9 Q5FBX1 Q5FBX2 Q75MR2 |
| Ensembl ID | ENSG00000122512 |
| Symbol | PMSL2 MLH4 PMSL2 HNPCC4 PMS2CL |
| Chromosome | 7 |
| Family | Belongs to the DNA mismatch repair MutL/HexB family. |
| Sequence |
MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463257 | LOC463257 | mismatch repair endonuclease PMS2 | 9598 | OMA, EggNOG | |
| Mouse | 18861 | Pms2 | PMS1 homolog2, mismatch repair system component | 10090 | MGI:104288 | Inparanoid, OMA, EggNOG |
| Rat | 288479 | Pms2 | PMS1 homolog 2, mismatch repair system component | 10116 | RGD:1305483 | Inparanoid, OMA |
| Dog | 479751 | PMS2 | PMS1 homolog 2, mismatch repair system component | 9615 | VGNC:54058 | Inparanoid, OMA, EggNOG |
| Horse | 100062380 | PMS2 | PMS1 homolog 2, mismatch repair system component | 9796 | VGNC:51217 | Inparanoid, OMA, EggNOG |
| Cow | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 9913 | OMA, EggNOG | ||
| Pig | 100514342 | PMS2 | PMS1 homolog 2, mismatch repair system component | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100027220 | PMS2 | PMS1 homolog 2, mismatch repair system component | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100081757 | PMS2 | PMS1 homolog 2, mismatch repair system component | 9258 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100564282 | pms2 | PMS1 homolog 2, mismatch repair system component | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | pms2 | PMS1 homolog 2, mismatch repair system component [Source:Xenbase;Acc:XB-GENE-998793] | 8364 | OMA, EggNOG | ||
| Zebrafish | 565276 | pms2 | PMS1 homolog 2, mismatch repair system component | 7955 | ZDB-GENE-030131-686 | Inparanoid, OMA, EggNOG |
| C. elegans | 179587 | pms-2 | PMS (Post Meiotic Segregation) family | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 36705 | Pms2 | CG8169 gene product from transcript CG8169-RA | 7227 | FBgn0011660 | Inparanoid, EggNOG |
| S.cerevisiae | 855642 | PMS1 | ATP-binding mismatch repair protein | 4932 | S000005026 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / Mismatch repair endonuclease PMS2
protein / nucleic acid binding / DNA binding protein / Mismatch repair endonuclease PMS2
DTO Classes
protein / Nucleic acid binding / DNA binding protein / Mismatch repair endonuclease PMS2
protein / Nucleic acid binding / DNA binding protein / Mismatch repair endonuclease PMS2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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