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SERPINE1

Description Plasminogen activator inhibitor 1

Gene and Protein Information

Gene ID 5054
Uniprot Accession IDs P05121 B7Z4S0 F8WD53 PAI
Ensembl ID ENSG00000106366
Symbol PAI1 PLANH1 PAI PAI1 PAI-1 PLANH1
Chromosome 7
Family Belongs to the serpin family.
Sequence
MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 472467 SERPINE1 serpin family E member 1 9598 VGNC:10053 OMA, EggNOG
Macaque 713883 SERPINE1 serpin family E member 1 9544 Inparanoid, OMA, EggNOG
Mouse 18787 Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 10090 MGI:97608 Inparanoid, OMA, EggNOG
Rat 24617 Serpine1 serpin family E member 1 10116 RGD:3249 Inparanoid, OMA, EggNOG
Dog 403476 SERPINE1 serpin family E member 1 9615 VGNC:46036 Inparanoid, OMA, EggNOG
Horse 100033931 SERPINE1 serpin family E member 1 9796 VGNC:22856 Inparanoid, OMA, EggNOG
Cow 281375 SERPINE1 serpin family E member 1 9913 VGNC:34476 Inparanoid, OMA, EggNOG
Pig 396945 SERPINE1 serpin family E member 1 9823 Inparanoid, OMA, EggNOG
Opossum 100017921 SERPINE1 serpin family E member 1 13616 Inparanoid, OMA, EggNOG
Anole lizard 100558317 serpine1 serpin family E member 1 28377 Inparanoid, OMA, EggNOG
Xenopus 100127732 serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 8364 XB-GENE-969639 Inparanoid, OMA, EggNOG
Zebrafish 100136840 serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 7955 ZDB-GENE-070912-60 Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    serine protease inhibitor    /    Plasminogen activator inhibitor 1
DTO Classes
protein    /    Enzyme modulator    /    Protease inhibitor    /    Serine protease inhibitor    /    Plasminogen activator inhibitor 1

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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