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| Description | Excitatory amino acid transporter 2 |
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Gene and Protein Information
| Gene ID | 6506 |
|---|---|
| Uniprot Accession IDs | P43004 B4DQE9 Q14417 Q541G6 U3KQQ4 |
| Ensembl ID | ENSG00000110436 |
| Symbol | EAAT2 GLT1 HBGT EAAT2 GLT-1 EIEE41 |
| Chromosome | 11 |
| Family | Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A2 subfamily. |
| Sequence |
MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKREK
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 450180 | SLC1A2 | solute carrier family 1 member 2 | 9598 | VGNC:7755 | OMA, EggNOG |
| Macaque | 574358 | SLC1A2 | solute carrier family 1 member 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20511 | Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 10090 | MGI:101931 | Inparanoid, OMA, EggNOG |
| Dog | 403750 | SLC1A2 | solute carrier family 1 member 2 | 9615 | VGNC:46262 | Inparanoid, OMA, EggNOG |
| Horse | 100067133 | SLC1A2 | solute carrier family 1 member 2 | 9796 | VGNC:23061 | Inparanoid, OMA, EggNOG |
| Cow | 541119 | SLC1A2 | solute carrier family 1 member 2 | 9913 | VGNC:34712 | Inparanoid, OMA, EggNOG |
| Pig | 100627068 | SLC1A2 | solute carrier family 1 member 2 | 9823 | OMA, EggNOG | |
| Opossum | 100009860 | SLC1A2 | solute carrier family 1 member 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100076652 | SLC1A2 | solute carrier family 1 member 2 | 9258 | Inparanoid, OMA | |
| Anole lizard | 100563190 | slc1a2 | solute carrier family 1 member 2 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100494868 | slc1a2 | solute carrier family 1 member 2 | 8364 | XB-GENE-1005169 | Inparanoid, OMA, EggNOG |
| Zebrafish | 335836 | slc1a2b | solute carrier family 1 (glial high affinity glutamate transporter), member 2b | 7955 | ZDB-GENE-030131-7779 | Inparanoid, OMA |
| C. elegans | 180641 | glt-1 | Excitatory amino acid transporter | 6239 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC1 family of amino acid transporters / Glutamate transporter subfamily / Excitatory amino acid transporter 2
protein / Transporter / SLC superfamily of solute carriers / SLC1 family of amino acid transporters / Glutamate transporter subfamily / Excitatory amino acid transporter 2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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