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| Description | Dual specificity mitogen-activated protein kinase kinase 5 |
|---|
Gene and Protein Information
| Gene ID | 5607 |
|---|---|
| Uniprot Accession IDs | Q13163 B4DE43 Q92961 Q92962 MAP kinase kinase 5 |
| Ensembl ID | ENSG00000137764 |
| Symbol | MEK5 MKK5 PRKMK5 MEK5 MAPKK5 PRKMK5 HsT17454 |
| Chromosome | 15 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. |
| Sequence |
MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 453532 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9598 | VGNC:7530 | OMA, EggNOG |
| Macaque | 711672 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 23938 | Map2k5 | mitogen-activated protein kinase kinase 5 | 10090 | MGI:1346345 | Inparanoid, OMA, EggNOG |
| Rat | 29568 | Map2k5 | mitogen activated protein kinase kinase 5 | 10116 | RGD:61890 | Inparanoid, OMA, EggNOG |
| Dog | 609559 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9615 | VGNC:42963 | Inparanoid, OMA, EggNOG |
| Horse | 100052849 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9796 | VGNC:19928 | Inparanoid, OMA, EggNOG |
| Cow | 100295732 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9913 | VGNC:31186 | Inparanoid, OMA, EggNOG |
| Opossum | MAP2K5 | mitogen-activated protein kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6845] | 13616 | Inparanoid, EggNOG | ||
| Platypus | 100085895 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 415557 | MAP2K5 | mitogen-activated protein kinase kinase 5 | 9031 | CGNC:50016 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100562970 | map2k5 | mitogen-activated protein kinase kinase 5 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 549042 | map2k5 | mitogen-activated protein kinase kinase 5 | 8364 | XB-GENE-960353 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100007679 | map2k5 | mitogen-activated protein kinase kinase 5 | 7955 | ZDB-GENE-030131-1517 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 5
protein / Kinase / Protein kinase / STE group / STE7 family / Dual specificity mitogen-activated protein kinase kinase 5
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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