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Targets(Human)
KDM1B

KDM1B

Description	Lysine-specific histone demethylase 1B

Gene and Protein Information

Gene ID	221656
Uniprot Accession IDs	Q8NB78 A2A2C5 A2A2C6 Q5TGV3 Q6AI15 Q6ZUU4 Q8N258 Q96EL7
Ensembl ID	ENSG00000165097
Symbol	AOF1 C6orf193 LSD2 AOF1 LSD2 C6orf193
Chromosome	6
Family	Belongs to the flavin monoamine oxidase family.
Sequence	MATPRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	462459	KDM1B	lysine demethylase 1B	9598	VGNC:7900	OMA, EggNOG
Macaque	704663	KDM1B	lysine demethylase 1B	9544		Inparanoid, OMA, EggNOG
Mouse	218214	Kdm1b	lysine (K)-specific demethylase 1B	10090	MGI:2145261	Inparanoid, OMA, EggNOG
Rat	306819	Kdm1b	lysine demethylase 1B	10116	RGD:1310701	Inparanoid, OMA, EggNOG
Dog	478733	KDM1B	lysine demethylase 1B	9615	VGNC:42319	Inparanoid, OMA, EggNOG
Horse	100066240	KDM1B	lysine demethylase 1B	9796	VGNC:19332	Inparanoid, OMA, EggNOG
Cow	513667	KDM1B	lysine demethylase 1B	9913	VGNC:30523	Inparanoid, OMA, EggNOG
Pig	100158047	KDM1B	lysine demethylase 1B	9823		Inparanoid, OMA, EggNOG
Opossum	100018222	KDM1B	lysine demethylase 1B	13616		Inparanoid, OMA, EggNOG
Platypus	100077241	KDM1B	lysine demethylase 1B	9258		Inparanoid, OMA, EggNOG
Chicken	420829	KDM1B	lysine demethylase 1B	9031	CGNC:9624	Inparanoid, OMA, EggNOG
Anole lizard	100552653	kdm1b	lysine demethylase 1B	28377		Inparanoid, OMA, EggNOG
Xenopus	100489838	kdm1b	lysine (K)-specific demethylase 1B	8364	XB-GENE-982183	Inparanoid, OMA, EggNOG
C. elegans	175493	amx-1	Amine oxidase family member 1	6239		Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    Lysine-specific histone demethylase 1B
protein    /    nucleic acid binding    /    oxidase    /    Lysine-specific histone demethylase 1B
protein    /    nucleic acid binding    /    methyltransferase    /    Lysine-specific histone demethylase 1B
protein    /    nucleic acid binding    /    DNA methyltransferase    /    Lysine-specific histone demethylase 1B

DTO Classes
protein / Epigenetic regulator / Eraser / Lysine demethylase / Lysine-specific demethylase / Lysine-specific histone demethylase 1B

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

🔙[Back to Target (Human)]

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