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NFE2L2

Description Nuclear factor erythroid 2-related factor 2

Gene and Protein Information

Gene ID 4780
Uniprot Accession IDs Q16236 B2RBU2 B4E338 E9PGJ7 Q53RW6 Q59HH2 Q96F71 NF-E2-related factor 2
Ensembl ID ENSG00000116044
Symbol NRF2 NRF2 HEBP1 IMDDHH
Chromosome 2
Family Belongs to the bZIP family. CNC subfamily.
Sequence
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGMQQDIEQVWEELLSIPELQCLNIENDKLVETTMVPSPEAKLTEVDNYHFYSSIPSMEKEVGNCSPHFLNAFEDSFSSILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISNSMPSPATLSHSLSELLNGPIDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSPSVASPEHSVESSSYGDTLLGLSDSEVEELDSAPGSVKQNGPKTPVHSSGDMVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGHRKTPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDVKKN
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 742622 NFE2L2 nuclear factor, erythroid 2 like 2 9598 VGNC:2708 OMA, EggNOG
Macaque 707606 NFE2L2 nuclear factor, erythroid 2 like 2 9544 Inparanoid, OMA, EggNOG
Mouse 18024 Nfe2l2 nuclear factor, erythroid derived 2, like 2 10090 MGI:108420 Inparanoid, OMA
Rat 83619 Nfe2l2 nuclear factor, erythroid 2-like 2 10116 RGD:620360 Inparanoid, OMA
Dog 478813 NFE2L2 nuclear factor, erythroid 2 like 2 9615 VGNC:43773 Inparanoid, OMA, EggNOG
Horse 100066816 NFE2L2 nuclear factor, erythroid 2 like 2 9796 VGNC:20708 Inparanoid, OMA
Cow 497024 NFE2L2 nuclear factor, erythroid 2 like 2 9913 VGNC:32036 Inparanoid, OMA, EggNOG
Pig 100516343 NFE2L2 nuclear factor, erythroid 2 like 2 9823 Inparanoid, OMA
Opossum 100026605 NFE2L2 nuclear factor, erythroid 2 like 2 13616 Inparanoid, OMA
Chicken 396014 NFE2L2 nuclear factor, erythroid 2 like 2 9031 CGNC:49604 Inparanoid, OMA
Anole lizard 100560087 nfe2l2 nuclear factor, erythroid 2 like 2 28377 Inparanoid, OMA
Xenopus 493217 nfe2l2 nuclear factor, erythroid 2 like 2 8364 XB-GENE-943926 Inparanoid, OMA, EggNOG
Zebrafish 360149 nfe2l2a nuclear factor, erythroid 2-like 2a 7955 ZDB-GENE-030723-2 Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    cytoskeletal protein    /    transcription factor    /    Nuclear factor erythroid 2-related factor 2
protein    /    cytoskeletal protein    /    nucleic acid binding    /    Nuclear factor erythroid 2-related factor 2
protein    /    cytoskeletal protein    /    hydrolase    /    Nuclear factor erythroid 2-related factor 2
protein    /    cytoskeletal protein    /    non-motor actin binding protein    /    Nuclear factor erythroid 2-related factor 2
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Nuclear factor erythroid 2-related factor 2

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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